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Cataract clinical trials

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NCT ID: NCT05564455 Completed - Clinical trials for Cataract; Surgery; Phacoemulsification; Biometry; Intraocular Lens Power

Comparison of SRK-T With Kane Formula for Prediction of Refractive Outcome After Phacoemulsification

Start date: June 17, 2021
Phase: N/A
Study type: Interventional

Cataract is a leading cause of blindness in the world. Cataract surgery is one of the most commonly performed ocular procedures. We aim to compare the newer generation biometry formula; the Kane formula with the commonly used SRK-T formula for intraocular power calculation in uneventful phacoemulsification surgery to assess the post-operative refractive outcomes at one month post-surgery.

NCT ID: NCT05530473 Completed - Clinical trials for Intraocular Lens Rotation

Combined Capsular Tension Ring and IOL Implantation for Management of Cataracts

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

This study included cataract patients who underwent intraocular lens (IOL) implantation with or without capsular tension ring (CTR), which aimed to evaluate the contribution of the use of CTR in clinical visual outcomes and rotational stability of IOL after cataract surgery.

NCT ID: NCT05529485 Completed - Cataract Clinical Trials

Quantification of Factors Influencing Endothelial Damage During Phacoemulsification

PREDICSPILOT
Start date: January 12, 2022
Phase:
Study type: Observational

The aim of this study is to determine the principal factors that influence endothelial cell loss three month post cataract surgery. Methods: Multi center observational Cohort study, inclusion period from 12/01/2022 to 10/06/2022. One hundred and seventy-five eyes of hundred and four patients who have appointment for cataract surgical indication were included. The percentage of corneal endothelial cell loss was quantified using specular microscopy before and 3 months after the surgery. 14 variables (pre-operative and intra-operative) that could be associated to endothelial cell injury were selected. A bivariate analysis of relationship between these factors and endothelial cell loss at 3 months was performed by simple linear regression (Wilcoxon and Fischer tests). Multivariate analysis was performed by multiple linear regression in order to identify the factors independently related to endothelial cell loss.

NCT ID: NCT05528172 Completed - Clinical trials for Corneal Edema After Cataract Surgery

A Study to Investigate the Safety and Efficacy of Ripasudil (K-321) Eye Drops After Cataract Surgery

Start date: August 4, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the safety and efficacy of K-321 in subjects after cataract surgery

NCT ID: NCT05526781 Completed - Cataract Clinical Trials

Visual Outcomes and Patient Satisfaction With Implantation of the Clareon Monofocal IOL With the New Clareon Manual Monarch IV IOL Delivery System

Start date: September 21, 2022
Phase:
Study type: Observational

To evaluate visual outcomes, in-the-bag placement and patient satisfaction in patients implanted with either Clareon monofocal or Clareon monofocal toric IOLs with the Monarch IV inserter and targeted for emmetropia.

NCT ID: NCT05511506 Completed - Cataract Clinical Trials

Cytokines in Femtosecond Laser-assisted Cataract Surgery

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The investigators performed the current study to compare: 1) the pain scores by Visual Analogue Scale; 2) the cytokines concentrations in aqueous humor by human cytokine antibody array; 3) the prostaglandin E2 (PGE2) concentrations by enzyme linked immunosorbent assay (ELISA); 4) the pupil behaviors by Image J between first-eye and second-eye in bilateral cataract patients undergoing sequential femtosecond laser-assisted cataract surgery (FLACS). To our knowledge, this is the first intraindividual study investigating contralateral effect in FLACS. The findings from the current study may broaden our understanding on the mechanism of sympathetic reaction, help to improve clinical performances, and provide strong clinical guidance for cataract surgeons.

NCT ID: NCT05510869 Completed - Cataract Clinical Trials

Evaluation of the Impact of Corneal Width on Surgically Induced Astigmatism (SIA) and Functional Results After Bimanual 1.4 mm Microincision Cataract Surgery (B-MICS), Coaxial 1.8 mm MICS (C-MICS) and 2.4 mm Small Incision Cataract Surgery (C-SICS).

MICS
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

The aim of the study is to compare functional results and complications of 3 methods of cataract phacoemulsification: bimanual 1.4 mm cataract surgery (B-MICS), coaxial 1.8 mm cataract surgery (C-MICS) and coaxial 2.4 mm small incision cataract surgery.

NCT ID: NCT05504343 Completed - Cataract Clinical Trials

Assessing The Visual Performance Of Hanita Lenses "Intensity SL" Intraocular Lens

Start date: December 27, 2021
Phase: N/A
Study type: Interventional

The Hanita Lenses Intensity SL IOL is intended for implantation in the capsular bag in the posterior chamber in order to replace the crystalline lens of the eye to attain visual correction of aphakia in adult patients in whom a cataractous lens has been removed, who desire improved uncorrected vision, useful near, intermediate and far visual functions, and reduced spectacle dependence.

NCT ID: NCT05495555 Completed - Cataract Clinical Trials

The Cutting Efficiency of Hybrid Tips in Different Grades of Cataract

Start date: August 3, 2022
Phase:
Study type: Observational

The objective is to assess the efficiency (as measured by phaco time, aspiration time, and fluid use) of the hybrid tip in removing cataract grade 3 & 4 in high and low intraocular pressure (IOP) settings.

NCT ID: NCT05494177 Completed - Cataract Clinical Trials

Comparison of Premium Monovision and Bilateral Implantation of Trifocal Diffractive Intraocular Lenses

Start date: August 1, 2022
Phase:
Study type: Observational [Patient Registry]

Primary objective of this study is to compare two presbyopia correction surgical techniques, specificaly premium monovision, in which the dominant eye is corrected with an extended depth of field intraocular lens and the non-dominant eye with a trifocal diffractive intraocular lens, and the bilateral implantation of trifocal diffractive intraocular lenses.