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Cataract clinical trials

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NCT ID: NCT05194150 Recruiting - Cataract Senile Clinical Trials

Performance of Two Intraocular Lenses With Extended Depth of Vision

Start date: January 3, 2022
Phase: N/A
Study type: Interventional

Comparison of the capsular bag performance of two extended depth of vision (EDOF) intraocular lenses (IOLs), the Rayone EMV and the Alcon Acrysof IQ Vivity, in a mini-monovision setting

NCT ID: NCT05191706 Recruiting - Cataract Clinical Trials

Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract

Start date: January 4, 2022
Phase: Phase 4
Study type: Interventional

A Phase 3/4, Prospective, Randomized, Active Treatment-Controlled, Parallel-Design, Multicenter Study to Evaluate the Safety of DEXYCUfor the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract

NCT ID: NCT05186298 Recruiting - Cataract Clinical Trials

Prospective Evaluation and Comparison of Bilateral Synergy Implants and Bilateral PanOptix Implants

Start date: November 2, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the AcrySof PanOptix Intraocular Lens (IOL) for binocular distance corrected near visual acuity (DCNVA) compared to TECNIS Synergy IOL. Presbyopia correcting diffractive intraocular implants (extended depth of focus, multifocal, and trifocal) provide cataract and refractive surgeons with an effective treatment means for allowing patients to experience increased spectacle independence post-cataract surgery.

NCT ID: NCT05161520 Recruiting - Cataract Clinical Trials

Impact of Capsular Tension Ring Implantation on Intraocular Lens Position

Start date: December 16, 2021
Phase: N/A
Study type: Interventional

This is a randomized controlled trial to investigate the effect of capsular tension ring (CTR) implantation on intraocular lens (IOL) tilt and decentration in cataract patients with high myopia.

NCT ID: NCT05158699 Recruiting - Cataract Clinical Trials

Effectiveness of Periocular Drug Injection in CATaract Surgery

EPICAT
Start date: October 13, 2021
Phase: Phase 3
Study type: Interventional

Cystoid macular edema (CME) is a major cause of suboptimal postoperative visual acuity after cataract surgery. Topical steroidal and nonsteroidal anti-inflammatory drugs (NSAIDs) are used to prevent CME. However, noncompliance with eye drops may compromise the effectiveness of treatment. Dropless periocular drug delivery during cataract surgery may improve the outcomes and cost-effectiveness of cataract surgery, and may alleviate the burden on homecare organizations.

NCT ID: NCT05157113 Recruiting - Surgery Clinical Trials

Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population

Start date: May 31, 2022
Phase: Phase 4
Study type: Interventional

The current postoperative cataract surgery eye drop regimen used at Zuckerberg San Francisco General Hospital (ZSFG) is a significant burden for its patient population, contributing to high rates of non-adherence and the development of postoperative complications. The investigators propose to replace this complex regimen with a single administration of intraocular antibiotic and subconjunctival steroid at the time of surgery. This pilot study will obtain the preliminary data required to eventually fully evaluate this innovation in postoperative care in a safety-net population with respect to postoperative outcomes, patient compliance, and patient and caregiver satisfaction.

NCT ID: NCT05148741 Completed - Clinical trials for Age-related Cataract

Evaluation of Capsular Bag Shape Changes After Plate-haptic Intraocular Lens Implantation by SS-OCT

Start date: July 1, 2020
Phase:
Study type: Observational [Patient Registry]

Evaluation of capsular bag shape changes after plate-haptic intraocular lens implantation by SS-OCT.

NCT ID: NCT05148507 Recruiting - Cataract Clinical Trials

Optimization of the Ocular Surface Prior to Cataract Surgery Using PROKERA

Start date: November 4, 2021
Phase: N/A
Study type: Interventional

The purpose of the study is to assess whether PROKERA can sufficiently stabilize the ocular surface prior to cataract surgery and improve post operative outcomes patients with moderate to severe dry disease.

NCT ID: NCT05147233 Recruiting - Clinical trials for Disorders of the Eye Following Cataract Surgery

OCS-01: A Phase 3 Study Evaluating the Efficacy and Safety of OCS-01 Eyedrops Compared to Vehicle for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery

Start date: June 1, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of OCS-01 Ophthalmic Suspension versus placebo (vehicle) in the treatment of inflammation and pain following cataract surgery.

NCT ID: NCT05146310 Completed - Cataract Clinical Trials

Prospective, Multicenter, Non-comparative Clinical Investigation to Support Safety & Effectiveness of I.SPACE®

PROMIR
Start date: December 6, 2021
Phase: N/A
Study type: Interventional

I.SPACE® is a hyaluronic acid injectable gel CE (European Conformity) marketed since 2010. It is indicated for use as a surgical aid in ophthalmic anterior segment surgery. The aim is to protect the corneal endothelium and maintains the intraocular space.The product should be instilled in the anterior chamber of the eye and adjusted according to the volume of the aqueous humour. In this study, 80 patients aged from 18 to 84 years' old at inclusion, who have at least one eye with cataract (mild to moderate severity) based on subjective ophthalmic examination by the investigator, who have given his/her informed consent and meet all the eligibility criteria, will be enrolled. Subjects will come to a total of 7 visits over a period of 3 months. Protection of corneal endothelium (Mean percent change of CEC density) after baseline injection will be assessed. Surgeon's satisfaction during cataract surgery, mean change in Intraocular Pressure (IOP), percentage of eyes with IOP spikes ≥ 30mm mmHg, corneal thickness, intraocular inflammation, Mean Snellen monocular Uncorrected Distance Visual Acuities (UCDVA), Best Corrected Distance Visual Acuities (BCDVA) and safety will be also assessed.