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Cataract clinical trials

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NCT ID: NCT01824927 Recruiting - Surgery Clinical Trials

Pain Expression in the Perioperative Period of Cataract Surgery

Start date: January 2013
Phase: N/A
Study type: Interventional

Patients having cataract extraction in the second eye under topical anesthesia with monitored anesthesia care often report increased pain and awareness relative to the first surgery in the fellow eye, despite similar operative and anesthetic conditions. The purpose of this study is to investigate the pathogenesis of this phenomenon.

NCT ID: NCT01793168 Recruiting - Clinical trials for Retinitis Pigmentosa

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

CoRDS
Start date: July 2010
Phase:
Study type: Observational [Patient Registry]

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, individuals and researchers to help in the advancement of research in over 7,000 rare diseases. The registry is free for patients to enroll and researchers to access. Visit sanfordresearch.org/CoRDS to enroll.

NCT ID: NCT01763593 Recruiting - Cataract Clinical Trials

Safety and Surgical Performance Study of Aurosleek Surgical Blades

Aurosleek
Start date: March 2013
Phase: N/A
Study type: Observational

To evaluate the safety and surgical effectiveness of surgical blades (Aurosleek) made by Aurolab.

NCT ID: NCT01726543 Recruiting - Cataract Clinical Trials

Safety and Efficacy of Canaloplasty and Non-penetrating Deep Sclerectomy With Phacoemulsification to Treat Glaucoma and Cataract

Start date: February 2011
Phase: N/A
Study type: Interventional

It is a comparative study of Safety and Efficacy of Canaloplasty and Non-penetrating Deep Sclerectomy Combined With Phacoemulsification to Treat Glaucoma and Cataract. It is a Randomised, Prospective Study.

NCT ID: NCT01677351 Recruiting - Pain Clinical Trials

Assessment of the Effect of Clonidine for Cataract Surgery

Start date: July 2011
Phase: Phase 2
Study type: Interventional

Clonidine, an agonist for alfa2 pre-synaptic, has been shown to be an effective adjuvant therapy for acute postoperative pain and has been shown an effect in sedative, intra-ocular and blood pressure and arrhythmias.The objective of this study is evaluating the analgesic effect of clonidine and its repercussion on arterial and intraocular pressure and arrhythmias for cataract surgery.

NCT ID: NCT01554761 Recruiting - Cataract Clinical Trials

Effect of Posterior Corneal Toricity on Refractive Outcome of Pseudophakia

Start date: February 2012
Phase: Phase 4
Study type: Interventional

This study is to evaluate the necessity of considering posterior corneal toricity on refractive outcome of patients with cataracts and corneal astigmatism after implantation of intraocular lenses. This is determined by comparing total corneal and refractive astigmatism,and by comparing the expected refractive result with actual refractive astigmatism postoperatively,using total corneal and anterior corneal astigmatism to calculate respectively.

NCT ID: NCT01441895 Recruiting - Cataract Clinical Trials

Corneal Sensation and Incidence of Dry Eye Post Refractive Cataract Extraction With FemtoSecond Laser

Start date: September 2011
Phase: N/A
Study type: Observational

The study objective is to assess changes in corneal sensation and dry eye signs and symptoms following cataract extraction/femtosecond arcuate relaxing incisions. Our clinical hypothesis is to determine if a combination of cataract surgery and femtosecond arcuate relaxing incisions lead to a reduction in corneal sensation and the onset or worsening of dry eye signs and symptoms.

NCT ID: NCT01403402 Recruiting - Clinical trials for Limb-Girdle Muscular Dystrophy

Congenital Muscle Disease Study of Patient and Family Reported Medical Information

CMDPROS
Start date: September 2009
Phase:
Study type: Observational [Patient Registry]

The Congenital Muscle Disease Patient and Proxy Reported Outcome Study (CMDPROS) is a longitudinal 10 year study to identify and trend care parameters, adverse events in the congenital muscle diseases using the Congenital Muscle Disease International Registry (CMDIR) to acquire necessary data for adverse event calculations (intake survey and medical records curation). To support this study and become a participant, we ask that you register in the CMDIR. You can do this by visiting www.cmdir.org. There is no travel required. The registry includes affected individuals with congenital muscular dystrophy, congenital myopathy, and congenital myasthenic syndrome and registers through the late onset spectrum for these disease groups. The CMDIR was created to identify the global congenital muscle disease population for the purpose of raising awareness, standards of care, clinical trials and in the future a treatment or cure. Simply put, we will not be successful in finding a treatment or cure unless we know who the affected individuals are, what the diagnosis is and how the disease is affecting the individual. Registering in the CMDIR means that you will enter demographic information and complete an intake survey. We would then ask that you provide records regarding the diagnosis and treatment of CMD, including genetic testing, muscle biopsy, pulmonary function testing, sleep studies, clinic visit notes, and hospital discharge summaries. Study hypothesis: 1. To use patient and proxy reported survey answers and medical reports to build a longitudinal care and outcomes database across the congenital muscle diseases. 2. To generate congenital muscle disease subtype specific adverse event rates and correlate with key care parameters.

NCT ID: NCT01278420 Recruiting - Cataract Clinical Trials

AMO's Tecnis™ Multifocal Intraocular Lenses (Tecnis MF), Alcon's ReStor Multifocal IOL

Start date: September 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR IOLs Six months post cataract surgery.

NCT ID: NCT01259349 Recruiting - Cataract Clinical Trials

Effect of Minimising Ultrasound Power to 1% During Cataract Surgery on Corneal Endothelium.

OCTOPUS
Start date: November 2010
Phase: Phase 3
Study type: Interventional

Coaxial microincision cataract surgery using 1% ultrasound is not inferior to standard coaxial microincision cataract surgery in patients of grade 0.1-6.0 immature senile cataract in terms of corneal endothelial safety.