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Carpal Tunnel Syndrome clinical trials

View clinical trials related to Carpal Tunnel Syndrome.

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NCT ID: NCT00929123 Completed - Clinical trials for Carpal Tunnel Syndrome

Mechanisms of Neural Mobilization in the Treatment of Chronic Pain

Start date: May 2007
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study was to determine the effect of a manual therapy technique (neural mobilization) on measures of clinical pain and function, experimental pain sensitivity, and on the function of the median nerve in individuals with carpal tunnel syndrome. The investigators hypothesized that individuals receiving a neural mobilization technique known to directly stress the median nerve would demonstrate greater improvements in clinical pain and function, experimental pain sensitivity, and median nerve function than those receiving a sham technique.

NCT ID: NCT00904202 Completed - Clinical trials for Carpal Tunnel Syndrome

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions

Start date: January 2003
Phase: Phase 4
Study type: Interventional

Patients with postherpetic neuralgia (PHN), diabetic neuropathy (DN), complex regional pain syndrome (CRPS), carpal tunnel syndrome, HIV neuropathy, idiopathic sensory neuropathy, or other peripheral neuropathy participated in a Phase IV clinical trial to assess the comparative efficacy and safety of Lidoderm monotherapy versus gabapentin monotherapy in treating a diverse group of peripheral neuropathic pain patients.

NCT ID: NCT00880295 Completed - Clinical trials for Carpal Tunnel Syndrome

Patient Outcomes With Endoscopic Versus Open Carpal Tunnel Release

Start date: March 23, 2009
Phase: N/A
Study type: Interventional

Although some surgeons prefer one technique rather than the other, both endoscopic and open carpal tunnel release procedures are accepted as standard of care surgeries to relieve carpal tunnel syndrome. The investigator's research is designed to evaluate the significant difference in patient satisfaction between endoscopically-released wrists and open-released wrists. The goal of the study is to compare the two techniques using the following criteria: 1. Primary outcome: patient satisfaction via surveys used in prior publications 2. Secondary outcome: length of time to return to work 3. Secondary outcome: clinical data for recovery from carpal tunnel syndrome including a thorough physical exam and EMG's 4. Secondary outcome: complication rates

NCT ID: NCT00856011 Completed - Clinical trials for Carpal Tunnel Syndrome

Nerve Morphology in Diabetic Patients

Start date: December 2003
Phase: N/A
Study type: Observational

The underlying basis of carpal tunnel syndrome and the basis of its increased incidence in diabetes are unknown. The aim of this study was to quantified pathology in an uncompressed nerve (posterior interosseous nerve in the forearm between diabetic and non-diabetic patients with CTS.

NCT ID: NCT00845325 Completed - Clinical trials for Carpal Tunnel Syndrome

Early Motion Following Carpal Tunnel Release

Start date: December 2008
Phase: N/A
Study type: Interventional

To objectively and subjectively assess two modes of commonly employed rehabilitation and confirm a superior method to treat patients following carpal tunnel release. One of the problems following carpal tunnel release (CTR) for carpal tunnel syndrome, and all hand surgeries, is the debilitation in the postoperative period. This relates to muscle atrophy and joint stiffness due to immobilization or relative inactivity in the postoperative period. Specifically, patients suffer increased days off from work, lost wages, and difficulties with activities of daily living affecting the patient and society at large. CTR is a very common procedure in hand surgery making it easy to study and important to optimize the postoperative care.

NCT ID: NCT00806871 Completed - Clinical trials for Carpal Tunnel Syndrome

Steroid Injection Treatment of Carpal Tunnel Syndrome

Start date: November 2008
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this study is to assess the efficacy of injecting steroid into the carpal tunnel in relieving symptoms of carpal tunnel syndrome for at least 1 year with outcomes measured with patient evaluated symptoms score.Out of the patients referred by primary care, those with a clinical diagnosis of CTS who have tried wrist splint and whose symptom severity is judged by the examining surgeon to warrant surgery are offered to be put on the waiting list for carpal tunnel release. This means a waiting time of approximately 3 months. Patients who give informed consent will be asked to attend the outpatient clinic for a physical examination followed by allocation to one of the three trial groups. Immediately following the allocation the patients will receive the assigned treatment.

NCT ID: NCT00803257 Completed - Clinical trials for Carpal Tunnel Syndrome

Effect of Lumbrical Stretching on Carpal Tunnel Syndrome

Start date: March 2008
Phase: N/A
Study type: Interventional

Symptoms of CTS occur when any condition decreases the size of the carpal canal or increases the volume of the structures within the carpal canal, compressing the median nerve. One cause of the symptoms of CTS is the incursion of the lumbrical muscles of the hand into the carpal canal. Individuals with CTS tend to have tight lumbrical muscles which increase this incursion, thereby increasing CTS symptoms. An intervention designed to reduce the incursion of the lumbrical muscles should have an effect on the symptoms of CTS. The purpose of this study is to systematically examine the effect of an intensive lumbrical muscle intervention, splinting to prevent lumbrical muscle incursion and lumbrical muscle exercises, on the symptoms of CTS. This project will be a randomized clinical trial to evaluate the effectiveness of a home program targeting the lumbrical muscles. One hundred and twenty subjects will be assigned to one of 4 groups: Group 1 will receive a home program of lumbrical muscle stretches combined with a lumbrical positioning splint; Group 2 will receive a home program of lumbrical muscle stretches combined with a night wrist cock-up splint; Group 3 will receive a home program of general stretches combined with a lumbrical positioning splint; and Group 4 will receive a home program of general stretches combined with a night wrist cock-up splint. After 1 month, 3 months, and 6 months the groups will be compared to determine if there is a significant reduction in symptoms between the groups.

NCT ID: NCT00775333 Completed - Clinical trials for Carpal Tunnel Syndrome

Nerve Entrapment in Diabetic Patients

Start date: December 2003
Phase: N/A
Study type: Observational

The aim of this study is in a prospective, consecutive series of diabetic patients with carpal tunnel syndrome, who are then age and gender matched with non-diabetic patients having idiopathic carpal tunnel syndrome to compare the clinical results after carpal tunnel release.

NCT ID: NCT00701233 Withdrawn - Clinical trials for Carpal Tunnel Syndrome

Botulinum Toxin for Carpal Tunnel Syndrome

Start date: June 2012
Phase: Phase 2
Study type: Interventional

To compare local steroid injections to local Botulinum toxin A injection in a double-blinded study.

NCT ID: NCT00694265 Completed - Clinical trials for Carpal Tunnel Syndrome

Sonographic Follow-up of Patients With Carpal Tunnel Syndrome Undergoing Surgical or Conservative Treatment

CTS
Start date: January 2002
Phase: N/A
Study type: Observational

In wrists with carpal tunnel syndrome (CTS) the sonographically measured largest cross-sectional area (CSA) of the median nerve is increased. We compared the changes in largest CSA in wrists undergoing surgical decompression and wrists undergoing conservative treatment of CTS.