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Cocoa Supplementation, Inflammaging, and Epigenetic Aging

Cardiovascular Diseases Clinical Trial

Official title:
Effect of Randomized Cocoa Supplementation on Inflammaging and Epigenetic Aging

Clinical Trial Summary

The COcoa Supplement and Multivitamin Outcomes Study (COSMOS; NCT02422745) is a randomized clinical trial of cocoa extract supplement (containing a total of 500 mg/d flavanols, including 80 mg. (-)-epicatechins), and a standard multivitamin supplement to reduce the risk of cardiovascular disease and cancer among men aged 60 years and older and women aged 65 years and older. This ancillary study is being conducted among participants in COSMOS and will examine whether the cocoa extract supplement or the multivitamin supplement has an anti-aging effect (epigenetic aging and inflammaging) and examining these findings in the context of CVD risk factors and outcomes.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05510375
Study type Interventional
Source Augusta University
Contact
Status Active, not recruiting
Phase Phase 4
Start date June 2015
Completion date September 30, 2023
View Details
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