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Cancer Survivor clinical trials

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NCT ID: NCT01439945 Completed - Breast Cancer Clinical Trials

Magnesium Oxide in Treating Postmenopausal Women With Hot Flashes and a History of Breast Cancer

Start date: September 2011
Phase: Phase 2
Study type: Interventional

RATIONALE: Magnesium oxide may help relieve hot flashes symptoms in women with a history of breast cancer. PURPOSE: This randomized clinical trial studies how well a high-dose or a low-dose of magnesium oxide works compared to placebo in treating menopausal women with hot flashes and a history of breast cancer.

NCT ID: NCT01347970 Active, not recruiting - Cancer Survivor Clinical Trials

Pharmacologic Reversal of Ventricular Remodeling in Childhood Cancer Survivors at Risk for Congestive Heart Failure (PREVENT-CHF): A Phase IIB Randomized Placebo-Controlled Trial

Start date: May 2012
Phase: Phase 2
Study type: Interventional

This randomized phase II trial studies the side effects and how well low-dose carvedilol works in preventing congestive heart failure (CHF) in younger cancer survivors exposed to high dose anthracyclines for management of childhood cancer. Carvedilol may help lower the risk of cardiovascular complications

NCT ID: NCT01298388 Not yet recruiting - Leukemia Clinical Trials

Study of Long-Term Outcomes of Patients With Acute Lymphoblastic Leukemia Who Were Enrolled as Children on Clinical Trials EORTC-58741, EORTC-58831, EORTC-58832, or EORTC-58881 Between 1971 and 1998

Start date: July 2011
Phase: N/A
Study type: Observational

RATIONALE: Studying medical records and collecting questionnaires from patients who were enrolled as children in clinical trials for acute lymphoblastic leukemia may help doctors learn about long-term effects of treatment and plan the best treatment. PURPOSE: This clinical trial is studying the long-term outcomes of patients with acute lymphoblastic leukemia who were enrolled as children on clinical trials EORTC-58741, EORTC-58831, EORTC-58832, or EORTC-58881 between 1971 and 1998.

NCT ID: NCT01231932 Recruiting - Breast Cancer Clinical Trials

Characterizing Fatigue Experienced by Cancer Patients Receiving Primary Treatment and Cancer Survivors

Start date: February 4, 2011
Phase:
Study type: Observational

Background: - Fatigue is a common side effect of cancer and its treatment. Up to 96% of patients with cancer have fatigue. The cause of fatigue in people with cancer or those receiving treatment is poorly understood, making fatigue hard to treat. More research is necessary to understand why cancer patients experience fatigue. Previous research has shown that fatigue may be caused by a number of factors, including problems with the immune system response of the body while undergoing cancer treatment. The researchers of this study are trying to understand how the immune system and other chemicals of the body change while a person receives cancer treatment and how these changes play a role in causing fatigue. The researchers are also interested in how a person s quality of life is affected by fatigue. Objectives: - To study fatigue in individuals who have cancer, are receiving cancer treatment, or have completed cancer treatment. Eligibility: - Individuals at least 18 years of age. - Receiving cancer treatment, OR completed primary treatment for cancer (e.g., cancer survivors), OR on active surveillance for localized cancer. Design: - This study involves an initial screening visit and up to three outpatient visits. - Participants will be screened with a medical history review (can be done virtually) and blood tests. A physical exam might also occur. - Participants undergoing cancer treatment that has a clear completion date, will have the following visits: - Before the start of treatment. - At the end of treatment. - At least 3 months after treatment ends. - Participants not receiving treatment, are cancer survivors, or undergoing cancer treatment that does not have a clear completion date, will have up to 3 visits: - Before the start of treatment or whenever you begin the study. - At least 3 months after your first visit. - At least 3 months after your second visit. - At each study visit, participants will complete the following tasks (some of the tasks can be done from home or virtually): - Questionnaires about physical activity, fatigue, depression, and quality of life (can be done at home or virtually). - Have blood drawn. - Physical activity device and journals to study how fatigue affects physical activity. - Optional tests: - Computer games testing your memory, attention, and ability to follow directions. - Hand grip strength test to evaluate physical strength. - Treatment will not be provided under this study.

NCT ID: NCT01098669 Completed - Clinical trials for Head and Neck Cancer

Impact of Secondary Lymphedema on Symptoms, Functional Status, and Quality of Life After Treatment in Patients With Head and Neck Cancer

Start date: December 2009
Phase: N/A
Study type: Observational

RATIONALE: Collecting information about the impact of lymphedema on symptoms, functional status, and quality of life after treatment in patients with head and neck cancer may help doctors learn more about the disease and plan the best treatment. PURPOSE: This phase I trial is studying the effects of secondary lymphedema on symptoms, functional status, and quality of life after treatment in patients with head and neck cancer.

NCT ID: NCT01077440 Terminated - Lymphoma Clinical Trials

Presence of Donor-Derived DNA in Semen Samples From Cancer Survivors Who Underwent Donor Stem Cell Transplant

Start date: February 2010
Phase: Phase 1
Study type: Observational

RATIONALE: Studying samples of semen from cancer survivors in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This phase I research study is looking at the presence of donor-derived DNA in semen samples form cancer survivors who underwent donor stem cell transplant.

NCT ID: NCT01032590 Withdrawn - Colorectal Cancer Clinical Trials

Internet-Based Weight-Loss Program for Colorectal Cancer Survivors

Start date: July 2009
Phase: N/A
Study type: Interventional

RATIONALE: A personalized Internet-based weight-loss program may help improve the quality of life for colorectal cancer survivors. PURPOSE: This randomized phase I trial is studying how well an Internet-based program works in helping colorectal cancer survivors lose weight.

NCT ID: NCT01008904 Completed - Breast Cancer Clinical Trials

Magnesium Oxide in Treating Hot Flashes in Menopausal Women With Cancer

Start date: July 2009
Phase: Phase 2
Study type: Interventional

RATIONALE: Magnesium oxide may help relieve hot flashes in women with cancer. PURPOSE: This phase II trial is studying how well magnesium oxide works in treating hot flashes in menopausal women with cancer.

NCT ID: NCT00993928 Terminated - Fatigue Clinical Trials

Home-Based Programs for Improving Sleep in Cancer Survivors

Start date: April 2010
Phase: Phase 2
Study type: Interventional

RATIONALE: Following a program that uses written materials and pre-recorded mp3 devices may help improve the sleep of cancer survivors. It is not yet known which home-based program is more effective in improving the sleep of cancer survivors. PURPOSE: This randomized phase II trial is comparing two home-based programs for improving sleep in cancer survivors.

NCT ID: NCT00972400 Recruiting - Breast Cancer Clinical Trials

Fatigue in Breast Cancer Survivors

Start date: January 2009
Phase: N/A
Study type: Observational

RATIONALE: Gathering information over time from blood samples and measurements of activity, sleep, mood, and cognition may help doctors learn more about fatigue in breast cancer survivors and plan the best treatment. PURPOSE: This clinical trial is studying fatigue in breast cancer survivors.