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NCT ID: NCT05215405 Available - Clinical trials for Relapsed Childhood Lymphoblastic Lymphoma

Expanded Access Program of Venetoclax and Navitoclax for Pediatric Patients With Relapsed or Refractory ALL or LL

Start date: n/a
Phase:
Study type: Expanded Access

The overall goal of this expanded access program is to provide Venetoclax and Navitoclax to patients with acute lymphocytic leukemia (ALL) or lymphoblastic lymphoma (LL) who have exhausted standard treatments.

NCT ID: NCT05219266 Available - Clinical trials for Acute Myeloid Leukemia

Managed Access Programs for PKC412, Midostaurin

Start date: n/a
Phase:
Study type: Expanded Access

The purpose of this registration is to list Managed Access Programs (MAPs) related to PKC4, Midostaurin.

NCT ID: NCT05222412 Available - Clinical trials for Paroxysmal Nocturnal Hemoglobinuria (PNH)

Managed Access Programs for LNP023, Iptacopan

Start date: n/a
Phase:
Study type: Expanded Access

The purpose of this registration form is to list all Managed Access Programs (MAPs) related to LNP023, Iptacopan

NCT ID: NCT05238311 Available - Multiple Myeloma Clinical Trials

Pre-approval Single-patient Expanded Access for Elranatamab (PF-06863135)

Start date: n/a
Phase:
Study type: Expanded Access

Provide pre-approval single-patient Expanded Access (Compassionate Use) of elranatamab for patients with relapsed/refractory multiple myeloma

NCT ID: NCT05269771 Available - Polycythemia Vera Clinical Trials

MAP to Provide Access to Ruxolitinib, for Patients With Polycythemia Vera

Start date: n/a
Phase:
Study type: Expanded Access

The purpose of this Cohort Treatment Plan is to allow access to ruxolitinib for eligible patients diagnosed with Polycythemia Vera. The patient's Treating Physician should follow the suggested treatment guidelines and comply with all local health authority regulations.

NCT ID: NCT05281484 Available - Clinical trials for Amyotrophic Lateral Sclerosis

Intermediate Expanded Access Protocol (EAP) CNMAu8.EAP02

Start date: n/a
Phase:
Study type: Expanded Access

The primary objective of the intermediate expanded access protocol is to provide access to the investigational product, CNM-Au8, to up to 300 people living with ALS (pALS). No formal clinical hypotheses are being evaluated with concurrent controls. Secondary objectives include assessment of the safety of CNM-Au8 treatment in pALS. Safety will be assessed through the frequency of serious adverse events (SAEs), treatment-emergent adverse events (TEAEs) assessed as 'severe', discontinuations due to TEAEs, and laboratory abnormalities assessed as clinically significant during routine clinical monitoring (as applicable).

NCT ID: NCT05338606 Available - Open-angle Glaucoma Clinical Trials

Expanded Access to Bimatoprost (Durysta)

Start date: n/a
Phase:
Study type: Expanded Access

This is an expanded access program (EAP) for eligible participants. This program is designed to provide access to Durysta (Bimatoprost) prior to approval by the local regulatory agency. Availability will depend on territory eligibility. A medical doctor must decide whether the potential benefit outweighs the risk of receiving an investigational therapy based on the individual patient's medical history and program eligibility criteria.

NCT ID: NCT05344508 Available - Clinical trials for Non-Cystic Fibrosis Bronchiectasis

An Expanded Access Study to Assess Brensocatib for Participants With Non-Cystic Fibrosis Bronchiectasis

Start date: n/a
Phase:
Study type: Expanded Access

The purpose of this study is to allow early access to brensocatib for participants with non-cystic fibrosis bronchiectasis (NCFBE) who have successfully completed the INS1007301 ASPEN Clinical trial.

NCT ID: NCT05346835 Available - Multiple Myeloma Clinical Trials

Expanded Access Program (EAP) for Ciltacabtagene Autoleucel (Cilta-Cel) Out-of-Specification (OOS) in Participants With Multiple Myeloma

Start date: n/a
Phase:
Study type: Expanded Access

The purpose of this expanded access program (EAP) is to provide ciltacabtagene autoleucel (cilta-cel) that does not meet the commercial release specifications of CARVYKTI and is not available via the local health care system in the country where the treatment is requested.

NCT ID: NCT05356052 Available - Clinical trials for Pulmonary Hypertension

Expanded Access for Patients With Pulmonary Hypertension Associated With Pulmonary Fibrosis

Start date: n/a
Phase:
Study type: Expanded Access

An expanded access program that provides INOpulse treatment to patients with serious disease or conditions associated with pulmonary hypertension associated with pulmonary fibrosis who are not able to participate in the Sponsor's ongoing Phase 3 REBUILD clinical.