Assessment of Suspected Intracranial Malignancy Using 3'-Deoxy-3'18 F-flourothymidine PET

Brain Tumor Clinical Trial

Official title:

Assessment of Suspected Intracranial Malignancy Using 3'-Deoxy-3'18 F-fluorothymidine Positron Emission Tomography

Clinical Trial Details — Status: Terminated

Administrative data

• NCT number: NCT00775320
• Other study ID #: FLT- Brain Study
• Status: Terminated
• Start date: October 2008
• Est. completion date: August 2010

Study information

• Verified date: November 2019
• Source: University of Oklahoma
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The primary objective of this study is to detect and quantify tumor cells of high grade malignant gliomas and metastatic brain lesions both before and after initial surgical resection in a cohort of newly diagnosed patients.

Description:

In this study, 35 patients will be selected to undergoing sequential imaging with FLT-PET. Prior to surgical resection, patients will undergo a preliminary FLT-PET. Additional FLT scans for a maximum of four scans.

Recruitment information / eligibility

• Status: Terminated
• Enrollment: 13
• Est. completion date: August 2010
• Est. primary completion date: August 2010
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 99 Years

Eligibility

Inclusion Criteria:

• 18 years or older

• Women must not be pregnant or breast feeding

• Histologic or strong radiologic suspicion of high grade malignant glioma or ogliometastatic tumor(s)

Exclusion Criteria:

• May not have received previous therapy for their malignancy

Related Conditions & MeSH terms

• Brain Neoplasms
• Brain Tumor

Intervention

Procedure:
• FLT-PET scan
Imaging test

Locations

Country	Name	City	State
United States	University Of Oklahoma Health Sciences Center	Oklahoma City	Oklahoma

Sponsors (2)

Lead Sponsor	Collaborator
University of Oklahoma	Midwest Medical Isotopes

Country where clinical trial is conducted

United States,