Bone Resorption Clinical Trial
Official title:
Biomaterial to Counteract Ridge Reduction Following the Removal of Multiple Adjacent Teeth. A Prospective Randomized Controlled Study.
An open, prospective, randomized, multicenter study focused on the ridge diminution in case of grafting of fresh extraction sockets with Bio-Oss Collagen, Bio-Gide (Geistlich Pharma, Wolhusen, Switzerland), placing Dentsply implants (Astra Tech System).
The removal of at least 2 adjacent teeth would cause more advanced hard tissue loss during healing than that occurring after removal of a single tooth with adjacent teeth present. In order to maintain the dimension of the ridge following tooth removal, bone grafts and bone substitutes have also been placed in the extraction socket. So far no data have been reported on the effect of removal of multiple adjacent teeth on bone loss at various aspects of the edentulous sites. Furthermore, the potential effect on ridge contraction of implant placement in multiple fresh extraction sites is not documented. Therefore, the objective of the study is to evaluate the possibility of counteracting un favourable ridge modeling after multiple tooth extractions by placing mineral bovine bone in the extraction sockets and covering the wound with a native collagen membrane. In addition, the possibility of placing implants in the grafted sites is evaluated after six month of healing. For these purpose 40 subjects with 2 or more fresh adjacent extraction sites in need of two or more implants replacing teeth will be enrolled. Ridge dimensional changes will be measured after 6 months of healing; marginal bone loss will be measured after 3-years follow-up from the baseline (prosthetic delivery). ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04073654 -
SA Versus SOI Surfaces for Single Implant-supported Crown
|
N/A | |
| Not yet recruiting |
NCT04345250 -
Bone Response to Exercise and Energy Restriction in Young Adults
|
N/A | |
| Completed |
NCT05533502 -
Combination Plant-Based Protein and Marine-Based Multi-Mineral Supplement and Bone Remodeling in Young Adults
|
N/A | |
| Completed |
NCT04279392 -
Healthy Body, Healthy Bones After Bariatric Surgery Trial
|
Phase 1/Phase 2 | |
| Recruiting |
NCT04548258 -
Bone Changes Assessment in Screw-Retained Maxillary Complete Denture With Electric Welded Framework Versus Cast One
|
N/A | |
| Withdrawn |
NCT04331028 -
Effect of Shock-wave Therapy on the Resorption and Bone Formation in Maxillary Postextraction Sockets
|
N/A | |
| Recruiting |
NCT06334159 -
Guided Bone Regeneration Using Fixed vs Non-Fixed Resorbable Collagen Membranes
|
N/A | |
| Completed |
NCT03888339 -
Influence of Abutment Shape on Peri-implant Marginal Bone Loss
|
N/A | |
| Completed |
NCT03026894 -
Association of Force Distribution and Bone Resorption
|
N/A | |
| Completed |
NCT02470611 -
Sodium Alendronate in Non Surgical Periodontal Therapy
|
Phase 4 | |
| Completed |
NCT00297830 -
Zoledronic Acid Versus Alendronate for Prevention of Bone Loss After Organ Transplantation
|
Phase 2/Phase 3 | |
| Recruiting |
NCT03431766 -
0.2% Chx Gel vs Implant Bacterial Contamination
|
N/A | |
| Recruiting |
NCT04141215 -
Allogeneic Bone Paste Versus Allogeneic Bone Powder
|
N/A | |
| Recruiting |
NCT05018130 -
Bio-Integrative Versus Metallic Screws for Calcaneus Osteotomies
|
N/A | |
| Completed |
NCT04790019 -
The Effects of Low Energy Availability and High Impact Jumping on Markers of Bone (re)Modelling in Females
|
N/A | |
| Recruiting |
NCT03889587 -
Innervation of Vascularized Iliac Transplant Avoids Resorption in Jaw Bone Reconstruction
|
N/A | |
| Completed |
NCT05804604 -
Bone Intake Proteins and Muscle Mass Deficiency in Proximal Femur Fractures
|
||
| Terminated |
NCT03089619 -
Alveolar Management Following Teeth Extraction
|
Phase 4 | |
| Completed |
NCT06049823 -
Alveolar Ridge Preservation With Different Grafting Strategies
|
N/A | |
| Recruiting |
NCT04377256 -
Hyaluronic Acid Effect on Xenogenic Bone Healing
|
Phase 4 |