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Bone Loss clinical trials

View clinical trials related to Bone Loss.

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NCT ID: NCT02025179 Completed - Osteoporosis Clinical Trials

12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)

Start date: January 2013
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if a second year of exposure to teriparatide in both subjects that received a year of teriparatide or teriparatide-placebo will result in a greater increase in bone mass density (BMD) compared to that seen in a single year's treatment. This study will also investigate 1) if a second year of teriparatide therapy will increase bone strength in people with chronic spinal cord injury (SCI) who previously received a year of teriparatide or teriparatide-placebo, 2) the number of participants with adverse events from teriparatide, and 3) the effects of teriparatide on serum markers of bone metabolism.

NCT ID: NCT01971268 Not yet recruiting - Bone Loss Clinical Trials

Compare the Success Rate of T3 Dental Implant (Biomet 3I) With or Without Platform-switch Concept

Start date: January 2014
Phase: N/A
Study type: Observational

In patients that received a T3 (Biomet 3I) dental implant, does the use of platform-switch concept compared to the use of platform-matched concept, refrain marginal bone loss during osseointegration phase (t=12 weeks =T1) and from then to final rehabilitation (t= placement of the final restoration = at 18 weeks=T2)

NCT ID: NCT01970826 Not yet recruiting - Bone Loss Clinical Trials

Compare Sterilized Clean vs Sterilized Aseptic Dental Implant Surgery

Start date: January 2014
Phase: N/A
Study type: Interventional

In patients that require dental implants , does performing the surgery in clean sterile field compared to aseptic field, produces more post-operatory complications, implant morbidity or patient discomfort ?

NCT ID: NCT01961635 Completed - Inflammation Clinical Trials

Healing of Bone/Soft Tissue to Different Abutment Biomaterials and the Impact on Marginal Bone Loss

Start date: January 2016
Phase: N/A
Study type: Interventional

In patients that require a dental implant, does zirconia compared to titanium, or cad-cam acrylic abutments, provide less inflammation, marginal bone loss or infection during the osseointegration period ?

NCT ID: NCT01878084 Completed - Bone Loss Clinical Trials

Bioactive Glass (Sol-gel) for Alveolar Bone Regeneration After Surgical Extraction

Start date: October 2013
Phase: N/A
Study type: Interventional

The purpose of the present research is to evaluate the effect of bioactive glass in bone regeneration immediately following extraction of mandibular and maxillary premolars.The hypothesis of the study assumes that this treatment would promote the healing of the extraction socket while preserving both the height and width of the bone. Furthermore, it would allow more effective tooth movement during orthodontic treatment.

NCT ID: NCT01700686 Completed - Obesity Clinical Trials

The Effect of Gastric Bypass Surgery on Gut Hormones Related to Bone Remodeling and Intestinal Growth.

Start date: October 2011
Phase: N/A
Study type: Observational

The overall purpose is to explore the link between the gut and the bones by investigating meal stimulated changes in the blood level of a number of hormones and markers related to intestinal growth and bone turnover in patients undergoing surgery for obesity (gastric bypass). The hormones will be measured in blood samples taken before and after surgery. The results are compared with changes in body weight and body composition as measured by DEXA scanning.

NCT ID: NCT01623908 Terminated - Breast Neoplasms Clinical Trials

Bone Loss Treatment From Adjuvant Zoledronate Efficacy

BLAZE
Start date: July 2011
Phase: N/A
Study type: Interventional

The main purpose of this study is to observe and assess the impact of adjuvant zoledronate on bone density in breast cancer patients. The second purposes: - The efficacy of adjuvant zoledronate - The safety of adjuvant zoledronate - The bone loss of breast cancer patients in Guangdong - The correlation between bone loss of breast cancer patients and treatment of disease in Guangdong

NCT ID: NCT01527526 Completed - Clinical trials for Cardiovascular Disease

Depot-medroxyprogesterone Acetate (DMPA) Contraceptive Method and Metabolism

DMPA
Start date: February 2011
Phase: N/A
Study type: Observational

Objective: The purpose of this study is to determine the etiology of the weight increase in Depot-medroxyprogesterone Acetate (DMPA) users. Method: Prospective study with 100 women, aged 18-40 years old and BMI < 30kg/m², paired with users of a non hormonal method follow for two years. Will be included only women who never used DMPA. There will be evaluated habit, blood pressure, anthropometric measure, distribution of corporal fat, lipids profile and glycemia parameters every six months. Thirty women and their control group will performed a euglycemic-hyperinsulinemic clamp to evaluate the resistance of insulin, adiponectin,neuropeptide Y, apolipoprotein A/B and arterial evaluation with ultrasound, intimal and media measure. Anova analysis for repeated samples. The metabolic alterations should elucidate the etiology, and the beginning of the sub clinical cardiovascular disease should be shown/discarded with the arterial evaluation.

NCT ID: NCT01394484 Completed - Osteoporosis Clinical Trials

Dairy Foods Compared to Dietary Supplements and Bone Health

FL-83
Start date: December 2010
Phase: N/A
Study type: Interventional

Does the consumption of dairy foods reduce the rate of bone loss in older women more than calcium and vitamin D supplements.

NCT ID: NCT01292395 Completed - Weight Loss Clinical Trials

Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency

Start date: September 2010
Phase: N/A
Study type: Interventional

Military personnel face many physiological challenges, including sustained physical activity and prolonged periods of negative energy balance. Chronic energy deficiency often results in a loss of skeletal muscle mass and can reduce overall bone health. Recent evidence suggests that dietary interventions that provide protein in excess of the current national dietary recommendation may confer protection against the negative effects of energy deficiency on the musculoskeletal system. The primary objective of this randomized, controlled study is to assess the effects dietary protein intake spanning the current acceptable macronutrient distribution range on musculoskeletal health following prolonged energy deficiency. Findings from this investigation will improve current understanding of dietary conditions necessary to reduce the damaging effects of caloric deficiency on musculoskeletal health in warfighters. Furthermore, given the rise in obesity in military populations, findings may aid in the development of nutritional weight management strategies that promote healthy weight loss without compromising musculoskeletal health.