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Clinical Trial Summary

A majority of Fire Department of New York (FDNY) World Trade Center (WTC) exposed rescue and recovery workers developed gastroesophageal reflux disease (GERD), a risk factor for Barrett's Esophagus (BE) and subsequent esophageal cancer. There is diminished health-related quality of life and productivity associated with aerodigestive diseases such as GERD and BE. This proposal will leverage the longitudinally phenotyped WTC exposed cohort, validate biomarkers of WTC-aerodigestive disease, and develop novel, noninvasive disease phenotyping of premalignant diseases such as BE, and identify potential targeted therapeutics to improve care.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05216133
Study type Observational
Source NYU Langone Health
Contact
Status Enrolling by invitation
Phase
Start date March 22, 2023
Completion date July 2024

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