Confocal Laserscanning Microscopy for Detection of Barretts Esophagus

Status Completed

Clinical Trial Summary

Four quadrant biopsies in regular ranges is the goldstandard in monitoring this disease. The ideal situation for the endoscopist is to visualize cellular structures, which implies having microscopic imaging available. A potential candidate to fill this gap could be confocal fluorescence microscopy (Cellvizio®-GI and Mauna Kea Technologies). To compare the gold standard with the confocal fluorescence microscopy for detection of metaplastic - or intraepithelial neoplastic changes of barrett-suspicious esophageal mucosa this study has been initiated.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

Barrett Esophagus

Clinical Trial Details

NCT number	NCT00449995
Study type	Interventional
Source	Technische Universität München
Contact
Status	Completed
Phase	N/A
Start date	March 2007
Completion date	November 2008

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT03554356` - Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE)	N/A
Completed	`NCT03015389` - Wide Area Transepithelial Sample Esophageal Biopsy Combined With Computer Assisted 3-Dimensional Tissue Analysis (WATS3D) For the Detection of High Grade Esophageal Dysplasia and Adenocarcinoma
Completed	`NCT03434834` - OCT Pilot in Esophagus	N/A
Terminated	`NCT04642690` - Nitrates and IL-8 in Barrett's Esophagus
Completed	`NCT03468634` - Raman Probe for In-vivo Diagnostics (During Oesophageal) Endoscopy	N/A
Recruiting	`NCT02310230` - An Evaluation of the Utility of the ExSpiron Respiratory Variation Monitor During Upper GI Endoscopy	N/A
Completed	`NCT00217087` - Endoscopic Therapy of Early Cancer in Barretts Esophagus	Phase 2
Completed	`NCT02284802` - Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy	N/A
Recruiting	`NCT05530343` - Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance	N/A
Active, not recruiting	`NCT04151524` - Classification of Adenocarcinoma of the Esophagogastric Junction
Completed	`NCT00955019` - Novel Method of Surveillance in Barrett's Esophagus	Phase 2
Terminated	`NCT00386594` - Pilot Study of Oral 852A for Elimination of High-Grade Dysplasia in Barrett's Esophagus	N/A
Completed	`NCT00576498` - Novel Imaging Techniques in Barrett's Esophagus	N/A
Completed	`NCT02688114` - Healing of the Esophageal Mucosa After RFA of Barrett's Esophagus	N/A
Recruiting	`NCT06071845` - Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples	N/A
Completed	`NCT02560623` - A Minimally-Invasive Sponge on a String Device for Screening for Barrett's Esophagus	N/A
Recruiting	`NCT05056051` - Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus	N/A
Recruiting	`NCT04001478` - Non-invasive Testing for Early oEesophageal Cancer and Dysplasia
Completed	`NCT03859557` - The Evaluation of Patients With Esophageal and Foregut Disorders With WATS (Wide Area Transepithelial Sample With 3-Dimensional Computer-Assisted Analysis) vs. 4-Quadrant Forceps Biopsy
Completed	`NCT04587310` - Does Laparoscopic Sleeve Gastrectomy Lead to Barrett's Esophagus, 5-year Esophagogastroduodenoscopy Findings: A Retrospective Cohort Study