PVP Iodine Effect on Post Debridement Bacteraemia — PJB 1  

Bacteraemia Post Debridement Clinical Trial

Official title: Effects of Ultrasonic Debridement With PVP-iodine Irrigation on Post-treatment Bacteraemia Compared to Ultrasonic Debridement With Water

Status Completed

Clinical Trial Summary

The study investigates the effect of supra- and subgingival rinsing of 10% PVP prior to ultrasonic debridement in patients with periodontitis (as compared to rinsing with water) in terms of post treatment bacteraemia.

Study design: Randomized split-mouth (cross-over) study on 20 generally healthy subjects.

Clinical Trial Description

Process:

Test treatment:

• 1 min mouthwash with 10% PVP-iodine

• 1 min subgingival rinsing with 10% PVP-iodine

• 1 min ultrasonic debridement with 10% PVP-iodine as cooling liquid

• blood sampling from the V.mediana cupidi

Control:

• 1 min mouthwash with water

• 1 min subgingival rinsing with water

• 1 min ultrasonic debridement with water as cooling liquid

• blood sampling from the V.mediana cupidi

lysis, culturing and analysis of bacteria in the samples ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Crossover Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Bacteraemia Post Debridement
• Bacteremia

• NCT number: NCT01647347
• Study type: Interventional
• Source: University of Zurich
• Status: Completed
• Phase: Phase 4
• Start date: August 2012
• Completion date: November 2013