Autistic Features in Relation to Motor Function and Quality of Life in Children With an Autism Spectrum Disorder

Autism Spectrum Disorder Clinical Trial

Official title:

Autistic Features in Relation to Motor Function and Quality of Life in Children With an Autism Spectrum Disorder

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05650489
• Other study ID #: autism spectrum disorder
• Status: Completed
• Start date: April 15, 2020
• Est. completion date: March 20, 2023

Study information

• Verified date: November 2023
• Source: Cairo University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Although motor limitations are not currently considered a as clinical manifestation of autism spectrum disorder, should not be ignored due to their high incidence and considerable influence on life quality functional activity

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: March 20, 2023
• Est. primary completion date: March 20, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 3 Years to 5 Years

Eligibility

Inclusion Criteria:

• Both sex,

• age ranges from 3 to 5 years,

• mild to moderate autistic features according to childhood autism rating scale ,

• were able to sit alone independently

Exclusion Criteria:

• Significant visual or auditory defects,

• history of cerebral palsy or psychiatric disorder (e.g attention deficit hyperactivity disorder)

Related Conditions & MeSH terms

• Autism Spectrum Disorder
• Autistic Disorder
• Child Development Disorders, Pervasive

Intervention

Other:
• assessment
correlation between Autistic features, motor function and quality of life

Locations

Country	Name	City	State
Egypt	Amira Mahmoud Abd-elmonem	Giza

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Autism Index	Gilliam autism rating scale: Items on the developmental subscale address behaviors and milestones in the first 36 months of life. Items on the first three behavioral subscales are rated on a four point like scale ranging from Never Observed (0) to Frequently Observed (3). After completing it, the examiner calculated the total raw scores then converted into scaled scores and percentile ranks according to the examiner's manual. Higher scaled scores on a subscale represent severe autistic behavior. Finally, the total scaled scores were calculated to measure the autism index according to the examiner's manual. The higher the autism index, the higher the probability the individual has autism and the more severe the autistic behavior	baseline assessment
Primary	Motor Development	The Peabody Developmental Motor Scales-Second Edition: The gross motor function domain will be assessed in the current study. The gross motor function domains contain four subtests. Reflexes, Stationary ,Locomotion and Object Manipulation .; Grading and Scoring of the PDMS-2 The therapist will ask the child to do a specific item and observes how the child is doing the task. Items are scored as 2, 1 or 0.; 0 = child cannot or will not attempt an item or the attempt does not indicate that the specific skill is emerging; child's performance shows a clear resemblance to item mastery criteria but does not fully meet the criteria or there are signs of an emerging skill; child performs item according to the criteria specified for mastering the skill	baseline assessment
Primary	Pediatric Quality of life Inventory Scale	Pediatric Quality of life Inventory Scale: The Arabic version will be used to assess quality of life. It contains questions about child's physical, emotional, social, and school functioning in the past 7 days. Parents/ child self-administered the quality of life after introductory instructions from the administrator. On the quality of life Generic Core Scales, for ease of interpretability, items are 22 reversed scored and linearly transformed to a 0-100 scale, so that higher scores indicate better Health-Related quality of Life. To reverse score, transform the 0-4 scale items to 0-100 as follows: 0-100, 1=75, 2= 50, 3= 25 and 4= 0. Finally, the Scale Score for each dimension and Total Scale Score were calculated	baseline assessment