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Arthritis clinical trials

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NCT ID: NCT05031104 Completed - Fatigue Clinical Trials

Low-energy Laser Applications in Patients With Juvenile Idiopathic Arthritis

Start date: October 21, 2018
Phase: N/A
Study type: Interventional

This study endeavored to evaluate the auxiliary effect of low-energy laser therapy (LLT) on pain, muscle performance, fatigue, and functional ability in children with juvenile idiopathic arthritis (JIA). Sixty patients with JIA were randomly allocated to the LLT group (n = 30, received LLT in addition to the standard exercise program) or the control group (n = 30, received standard exercise program only). Both groups were assessed for pain intensity, muscle performance, fatigue perception, and functional status.

NCT ID: NCT05019547 Completed - Clinical trials for Axial Spondyloarthritis

The Turkish Version of the Inflammatory Arthritis Facilitators and Barriers to Physical Activity

Start date: September 1, 2021
Phase:
Study type: Observational

Our aim in this study is to translate the Inflammatory Arthritis Facilitators and Barriers to Physical Activity (IFAB) Questionnaire which was developed to determine the factors that facilitate and prevent individuals for physical activity for patients with inflammatory arthritis into Turkish language. Also, our aim is to evaluate the validity and reliability of the IFAB Questionnaire in the Turkish population, and to perform a cultural adaptation if necessary at the same time. Determining the factors that facilitate and prevent individuals for physical activity interventions with rheumatic diseases and then designing physical activity programs considering these factors may play an important role in reducing the symptoms caused by the disease and increasing their quality of life.

NCT ID: NCT05000216 Completed - Clinical trials for Rheumatoid Arthritis (RA)

COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders

Start date: August 13, 2021
Phase: Phase 2
Study type: Interventional

This is a randomized, multi-site, adaptive, open-label clinical trial comparing the immune response to different additional doses of COVID-19 vaccine in participants with autoimmune disease requiring IS medications. All study participants will have negative serologic or suboptimal responses (defined as a Roche Elecsys® Anti-SARS-CoV-2 S result ≤200 U/mL) or a low immune response (defined as a Roche Elecsys® Anti-SARS-CoV-2 S result >200 U/ml and ≤2500 U/mL) to their previous doses of COVID-19 vaccine. The study will focus on 5 autoimmune diseases in adults: - Systemic Lupus Erythematosus (SLE) - Rheumatoid Arthritis (RA) - Multiple Sclerosis (MS) - Systemic Sclerosis (SSc), and - Pemphigus. This study will focus on 4 autoimmune diseases in pediatric participants: - Systemic Lupus Erythematosus (SLE) - Juvenile Idiopathic Arthritis (JIA) - Pediatric-Onset Multiple Sclerosis (POMS) - Juvenile Dermatomyositis (JDM)

NCT ID: NCT05000086 Completed - Clinical trials for Arthritis, Psoriatic

A Pilot Study of Technetium [99Tc] Methylene Diphosphonate in the Treatment of Psoriatic Arthritis

Start date: June 1, 2019
Phase: Phase 4
Study type: Interventional

This study is aim to evaluate the efficacy and safety of technetium [99Tc] methylene diphosphonate (99Tc-MDP, trade name: Yunke) in the treatment of psoriatic arthritis.

NCT ID: NCT04999683 Completed - Clinical trials for Rheumatoid Arthritis

Effect of Anti-inflammatory (ITIS) Diet in Rheumatoid Arthritis

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

to study the effect of anti-inflammatory diet on clinical and biological outcomes in rheumatoid arthritis

NCT ID: NCT04991753 Completed - Clinical trials for Arthritis, Rheumatoid

A Proof-of-concept Study of the Efficacy and Safety of Nipocalimab in Participants With Active Rheumatoid Arthritis

Start date: October 14, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of nipocalimab versus placebo in participants with moderate to severe active rheumatoid arthritis (RA).

NCT ID: NCT04985812 Completed - Clinical trials for Rheumatoid Arthritis

A Study of JNJ-67484703 in Participants With Active Rheumatoid Arthritis

Start date: October 18, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate safety and tolerability of JNJ-67484703 administrations in participants with active rheumatoid arthritis (RA).

NCT ID: NCT04969432 Completed - Arthritis Knee Clinical Trials

Effectiveness of Client-centered Intervention in After Total Knee Arthroplasty

Start date: January 7, 2021
Phase: N/A
Study type: Interventional

The current study was conducted to comparison of the Client-centered (CC) intervention with face-to-face (FF) and TR methods after Total Knee Arthroplasty (TKA). The pilot study was planned to examine the impact of the CC intervention on quality of life, perceived occupational performance and satisfaction. The current study was designed according to the CONSORT statement, which provides a standardized method for randomized controlled trial (RCT) design. Approval for the study was granted by the Local Ethics Committee. Written informed consent was obtained from all participants prior to the study.

NCT ID: NCT04956393 Completed - Osteoarthritis Clinical Trials

The SOAR (Stop OsteoARthritis) Program Proof-of-Concept Study

SOARPOC
Start date: September 1, 2021
Phase: N/A
Study type: Interventional

Adolescents and young adults who hurt their knees playing sports or doing recreational activities can develop joint damage, muscle weakness, inactivity, and weight gain which might lead to an increased risk of osteoarthritis (OA), a disabling joint condition in their later lives. Despite knowing that muscles and joints benefit from exercise, there is no proven exercise-based treatments to delay or even halt the onset of OA after a knee joint injury. The current study will assess if a physiotherapist-guided intervention called Stop OsteoARthritis (SOAR) improves knee muscle strength, physical inactivity, knee-related self-efficacy, and knee-related quality of life in people at risk for osteoarthritis due to a past knee injury. A total of 70 former knee injury participants will be randomly assigned to two groups. One group will immediately start a 16-week SOAR program, while the second will wait for 9-weeks before starting an 8-week SOAR program. Trained physiotherapists will deliver the SOAR program with videoconferencing. The study hypothesis is that participating in the 8-Week SOAR program will improve the knee muscle strength, physical activity levels, knee-related self-efficacy and knee-related quality of life in people discharged from regular healthcare after a sports knee injury. The findings will help researchers understand the ideal length of the program for a future clinical trial in real-world settings.

NCT ID: NCT04948775 Completed - Clinical trials for Rheumatoid Arthritis

Cervical Stabilization Exercises in Patients With Rheumatoid Arthritis

Start date: November 28, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness of cervical stabilization exercises on cervical positioning error in rheumatoid arthritis.