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Apnea clinical trials

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NCT ID: NCT00456339 Terminated - Clinical trials for Obstructive Sleep Apnea Syndrome

Systemic Steroids Plus Antibiotics in Sleep Apnea Syndrome in Children

Start date: July 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to investigate the effect of treatment with a steroid and antibiotic on the size of the tonsils and symptoms of children with OSAS.

NCT ID: NCT00404807 Terminated - Heart Failure Clinical Trials

Cardiac Function After CPAP Therapy in Patients With Chronic Heart Failure and Sleep Apnea. A Multicenter Study

Start date: January 2001
Phase: N/A
Study type: Interventional

The role of continuous positive airway pressure (CPAP) in cardiac function in patients with CSA and OSA has been studied with varying results. Nevertheless, it is not clear whether CPAP treatment for respiratory sleep disorders in CHF could slow down deterioration or improve the cardiovascular function. In an attempt to yield further insight into this subject, we undertook a multicentre study to analyze the role of CPAP therapy (optimal vs sham) in the LVEF and in other cardiac measurements in patients with CHF.Aim. We evaluated in a randomized multicentre placebo (sham-CPAP) controlled study the effect of CPAP treatment on the left ventricle ejection fraction (LVEF) among other cardiological related variables.

NCT ID: NCT00394550 Terminated - Clinical trials for Sleep Apnea, Obstructive

Treatment of Children With Obstructive Sleep Apnea and Laryngomalacia: the Role of Laser Supraglottoplasty

Start date: January 2002
Phase: N/A
Study type: Interventional

This is a research study of the effect of treating laryngomalacia (floppiness of tissue on top of the voice box that can possibly block breathing) found in association with obstructive sleep apnea (blockage of breathing while sleeping). The purpose of this study is to determine which is the best treatment for children with obstructive sleep apnea and laryngomalacia: adenotonsillectomy alone or adenotonsillectomy with laser supraglottoplasty (removal of tissue on top of the voice box to open the airway).

NCT ID: NCT00313092 Terminated - Glaucoma Clinical Trials

Obstructive Sleep Apnea Syndrome in Glaucoma

Start date: January 2005
Phase: N/A
Study type: Observational

The aim of the study is to determine if plasma matrix-metalloproteinase activity can predict glaucoma in patients with OSAS and if the level of plasma matrix-metalloproteinase activity will decrease after one month of nCPAP-treatment.

NCT ID: NCT00282815 Terminated - Stroke Clinical Trials

Sleep Apnea Treatment After Stroke (SATS)

Start date: September 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if treating stroke patients who have obstructive sleep apnea with continuous positive airway pressure will improve symptoms caused by the stroke.

NCT ID: NCT00203996 Terminated - Clinical trials for Obstructive Sleep Apnea

Polycystic Ovary Syndrome (PCOS) and Sleep Apnea

Start date: September 2003
Phase: Phase 4
Study type: Interventional

Polycystic ovary syndrome (PCOS) affects 5-10% of women in the United States. Its onset is usually at the time of puberty with manifestations of menstrual irregularity, hirsutism, and obesity. Women with PCOS suffer at an early stage of adulthood from all of the components of the metabolic syndrome, a syndrome that typically has its peak in mid-life in other subject populations. Women with PCOS are more insulin resistant than weight-matched control women and have exceptionally high rates of early-onset impaired glucose tolerance and type 2 diabetes, as well as a substantially elevated risk for hypertension, dyslipidemia, coronary, and other vascular diseases. While recent evidence indicates that the prevalence of sleep-disordered breathing (SDB) is 30-40 fold higher in PCOS than in weight-matched control women, the possible role of SDB in causing the increased metabolic and cardiovascular risks of PCOS has not been evaluated. The overall objective of the proposed study is to analyze the direction of causality between sleep disturbances and markers of the metabolic syndrome in PCOS.