Clinical Trials Logo

Clinical Trial Summary

Anterior cruciate ligament (ACL) tears are one of the most common injuries of the knee. In today's world, due to developing sports industry , the increase in sports traumas of both genders and ages ACL injuries and treatments are given major priority. The success of anterior cruciate ligament (ACL) reconstruction depends on many factors, including the mechanical properties of the graft, positioning of the proper femoral and tibial tunnel, fixation methods and the postoperative rehabilitation. The tendon grafts can be fixed on the femoral side using several fixation devices, including cortical suspension devices, cross pins, and interference screws. Femoral fixation via Cortical button in a suture loop provides the highest primary stability, and therefore, has become increasingly popular among orthopaedic surgeons. Adjustable and fixed Femoral cortical loops are commonly used for femoral fixation. In this sudy we aimed to compare clinical and functional outcomes of three different techniques of suspensory femoral fixation in ACL reconstruction.


Clinical Trial Description

This study has been planned as a prospective randomized clinical trial. We used a completely computer-generated list in order to randomize all participants to receive one of two treatments (www.random.org/sequences/). Anterior Cruciate Ligament tear diagnosis will be made by physical examination and magnetic resonance imaging. Participants who agree to be enrolled to study will be examined one day prior to surgery. Patients are randomly divided into 3 groups, after tibial fixation of the hamstring autograft, 3 different techniques will be used in the femoral fixation phase. The first group will be without knotting and retensioning the graft. In the second group, The graft will be retensioned after tibial fixation. In the third group femoral loop will be retensioned and knotted after tibial fixation. All the surgeries will be performed by the same senior surgeon experienced in sports medicine surgery under regional anesthesia with patient in supine position. All participants will receive a standard postoperative rehabilitation program starting immediately after surgery with closed chain exercises and quadriceps strengthening and walking. The operated lower extremity won't be placed in a brace and patient allowed for full weight walking with a pair of crutches. Postoperative evaluations will be performed regularly at 12 months postoperatively . To assess knee stability, KT-1000 measurement will be applied to both extremities in each group and clinical scores ( lysholm knee score, IKDC ) will be measured. Furthermore, to evaluate flexor and extensor muscle group around knee, isokinetic tests will be applied to patients in sitting position to analyse peak torque and total work done values. ;


Study Design


Related Conditions & MeSH terms

  • ACL Injury
  • Anterior Cruciate Ligament Injuries
  • Anterior Cruciate Ligament Rupture
  • Rupture

NCT number NCT04677218
Study type Interventional
Source Istanbul University
Contact
Status Completed
Phase N/A
Start date January 15, 2018
Completion date November 15, 2021

See also
  Status Clinical Trial Phase
Recruiting NCT05487768 - Functional Connectivity After Anterior Cruciate Ligament Reconstruction N/A
Recruiting NCT04390035 - BFRT in Adolescents After ACL Reconstruction N/A
Recruiting NCT02740452 - Anterior Cruciate Ligament Rupture N/A
Not yet recruiting NCT02555917 - Comparison of Remnant Preserving Versus Remnant Resecting Anterior Cruciate Ligament Reconstruction N/A
Active, not recruiting NCT00529958 - Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction N/A
Completed NCT05109871 - Reliability and Validity of Inline Dynamometry Study for Measuring Knee Extensor Torque N/A
Not yet recruiting NCT06048848 - FNB in ACL Recon Under GA N/A
Not yet recruiting NCT06048874 - FNB in ACL Recon Under SA N/A
Terminated NCT03529552 - Evaluation After Reconstruction of the Anterior Cruciate Ligament of the Knee Using the Bioresorbable Interference Screw (SMS): Resorbability, Per- and Post-operative Complications and Articular Functional Recovery. N/A
Completed NCT04285853 - Are Opioids Needed After ACL Reconstruction Phase 4
Recruiting NCT04088227 - Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears Phase 2
Active, not recruiting NCT03671421 - Number One Overall Graft Pick? Hamstring vs Bone-Patellar-Tendon-Bone vs Quadriceps Tendon N/A
Not yet recruiting NCT04953676 - A Clinical Trial of the Round-tunnel and Flat-tunnel Technique of ACL Reconstruction N/A
Not yet recruiting NCT04957706 - Diagnostic Study of ACL Rupture With Anterior Drawer Test at 90° of Hip Flexion
Enrolling by invitation NCT03365908 - Pain Management of ACL Reconstruction N/A
Recruiting NCT06030791 - BTB Graft Harvest and Donor Site Morbidity After ACL Reconstruction
Recruiting NCT03950024 - Improvement of Knowledge About the Arthrogenic Muscle Inhibition in the Aftermath of Knee Trauma. N/A
Recruiting NCT03229369 - Association of ALL and ACL Reconstruction Versus Isolated ACL Reconstruction in High-risk Population: a RCT. N/A
Completed NCT01267435 - Evaluation of Tibial and Femoral Tunnel Position After Arthroscopic Reconstruction of the Anterior Cruciate Ligament Phase 2
Completed NCT05057442 - The Effects of Remnant-Preserving Anterior Cruciate Ligament Reconstruction on Proprioception and Functionality