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Alveolar Bone Loss clinical trials

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NCT ID: NCT04274244 Not yet recruiting - Clinical trials for Chronic Periodontitis

Comparison of Clinical and Radiographic Parameters in the Application of Cross-linked Hyaluronic Acid 1.8% and Enamel Matrix Derivative in Periodontal Regeneration.

Start date: March 1, 2020
Phase: Phase 4
Study type: Interventional

The aim of this study is to compare the effectiveness in periodontal regeneration of cross-linked hyaluronic acid at 1.8% (Hyadent BG®) with enamel matrix derivative (Emdogain®) in periodontal bone defects evaluating their clinical and radiographic variables.

NCT ID: NCT04262999 Recruiting - Alveolar Bone Loss Clinical Trials

Bone Mineral Density and Periodontal Status in Patients on Antiepileptic Drug

Start date: January 1, 2020
Phase:
Study type: Observational

Assessment of bone mineral density and periodontal parameters in patients with epilepsy. Comparative evaluation of bone mineral density and levels of marginal alveolar bone in patients with epilepsy on monotherapy, combination therapy, and systemically healthy individuals.Comparative evaluation of periodontal parameters in all the patients who are on monotherapy and combination therapy and in systemically healthy individuals.

NCT ID: NCT04243421 Completed - Clinical trials for Alveolar Process Atrophy

Marginal Bone and Soft Tissue Alterations After Use of OsseoSpeed EV Profile Implants

Start date: February 1, 2016
Phase: N/A
Study type: Interventional

Evaluation of the marginal bone and soft tissue alterations after the OsseoSpeed™ EV Profile implants placement in anterior maxilla. The following parameters will be tested: - pink esthetic score - at the temporary crown delivery, at the final crown delivery, 6 months post final crown delivery - papilla index - at the temporary crown delivery, at the final crown delivery, 6 months post final crown delivery - changes in radiographic marginal bone levels and width at buccal and palatal aspects: differences between baseline (the day of surgery) and 1-year post-op measurements on CBCT will be made.

NCT ID: NCT04229719 Recruiting - Alveolar Bone Loss Clinical Trials

Effect of Topical Melatonin Application on Dental Implant Osseointegration and Marginal Bone Level

Start date: November 1, 2019
Phase: Phase 3
Study type: Interventional

Background: Melatonin (N-acetyl-5-methoxy-tryptamine) is an indoleamine synthesized and secreted by the pineal gland and other organs, such as the retina, bone marrow, and intestines in a circadian pattern. Some authors claimed that Melatonin induces bone formation, increase bone density, and bone implant contact. According to animal and human studies the melatonin can be used topically during implant placement to increase bone implant contact and reduce marginal bone loss. Purpose: The aim of this study was to evaluate the effect of the topical administration of melatonin on osseointegration of dental implants and in minimize marginal bone loss. Materials and Methods: Twenty single-piece endosseous implants (Dentium Co, Korea) will use to restore missing lower teeth from canine to first molar area. The study will be split-mouth technique, each patient serve as his own control (served into 2 groups), the study side (topical application of melatonin in the implant side), and the control side (no melatonin in the other implant side of the same patients).The primary and secondary stability of dental implant will be evaluated by periotest M device and measure bone level as baseline immediately after implant placement and after 6 months follow up by CBCT.

NCT ID: NCT04214041 Completed - Alveolar Bone Loss Clinical Trials

Autologous Fat Grafting Versus Subepithelial Connective Tissue Graft for Volume Augmentation

Start date: December 17, 2018
Phase: N/A
Study type: Interventional

The aim of this study was to evaluate the effectiveness of autologous fat as a grafting material for soft tissue volume augmentation of localized horizontal ridge defects in humans.

NCT ID: NCT04190576 Completed - Alveolar Bone Loss Clinical Trials

Minimally Invasive Ridge Augmentation

Start date: November 10, 2017
Phase: N/A
Study type: Interventional

The present study is a human, prospective, randomised controlled clinical trial conducted to explore the outcome of a minimally invasive ridge augmentation technique with and without low level laser therapy. The trial is in accordance with the Consolidated Standards of Reporting Trials (CONSORT) criteria, 2010.

NCT ID: NCT04160689 Completed - Bone Loss Clinical Trials

Influence of the Implant Connection on Facial Tissues Maturation

Start date: November 1, 2018
Phase: Phase 4
Study type: Interventional

The substitution of a tooth with a fixture often induces undesired morphological changes, resulting in a deterioration of the aesthetic appearance. The purpose of this study is to compare the soft tissue behavior next to two different implant connections: 5° (group 1) and 35° hexed (group 2), conical, internal with switching platform design after 12 months of functional provisionalization

NCT ID: NCT04144322 Active, not recruiting - Bone Loss, Alveolar Clinical Trials

Short Dental Implants (5 mm) Versus Long Dental Implants (10 mm)

Start date: October 14, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the survival rate of 5 mm short implants compared to longer implants (10 mm) placed in sinus-grafted sites. Primary aim: Compare bone loss between the two groups Secondary aim: Compare surgical time and patient-reported outcomes (satisfaction and post-operative pain)

NCT ID: NCT04136509 Completed - Alveolar Bone Loss Clinical Trials

Microarchitecture of the Augmented Bone Following Sinus Elevation

MAB
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

In this prospective randomized clinical study sinus floor elevation procedures are preformed using different biomaterials with the lateral window technique. After a 6-month healing, at the time of dental implant placement bone core biopsy samples are harvested. The samples undergo micro-Ct and histomorphometric analysis.

NCT ID: NCT04133090 Completed - Alveolar Bone Loss Clinical Trials

Comparison of Autogenous Bone Graft and Screw Tent-Pole Technique on Atrophic Mandible

Start date: April 11, 2016
Phase: N/A
Study type: Interventional

The purpose of the present study was to assess the effect of injectable platelet-rich fibrin (i-PRF) enriched with allograft on alveolar bone regeneration when compared with autogenous block bone graft, in the same participants. The study was designed as a split-mouth randomized controlled trial. The patients were randomly assigned to one of two surgical groups: the test group with i-PRF enriched particulate allograft using the screw tent-pole technique; and the control group with autogenous block bone harvested from the ramus area. All augmentation sites covered by leukocytes-PRF (L-PRF) membrane. The primary outcome variable of this study was the radiographic and histologic data collected at postoperative 6 months. The secondary outcome variable was nerve alterations and implant survival.