ED50 of Dexmedetomidine to Prevent Emergence Agitation in Children

Status Recruiting

Clinical Trial Summary

There are several recommended doses of dexmedetomidine for prevention of emergence agitation in children. In this study, the investigators examine ED50 in prevention of emergence agitation after tonsillectomy or adenoidectomy in children.

Clinical Trial Description

To investigate ED50, Dixon's up and down method will be used. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01374737
Study type	Interventional
Source	Seoul National University Hospital
Contact	Hee-Soo Kim, M.D., PhD
Phone	82220723659
Email	dami0605@snu.ac.kr
Status	Recruiting
Phase	Phase 4
Start date	June 2011
Completion date	February 2012

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02525991` - Phase IV to Evaluate the Safety of Self-administered ADASUVE® in Agitated Patients Outside the Hospital Setting	Phase 4
Recruiting	`NCT05557409` - A Study to Assess the Efficacy and Safety of AXS-05 in Subjects With Alzheimer's Disease Agitation	Phase 3
Completed	`NCT01976754` - Safety Study of Dexmedetomidine in Septic Patients	N/A
Completed	`NCT01217541` - Collaboration Between Department of Old Age Psychiatry and Nursing Homes	N/A
Withdrawn	`NCT00786318` - Ziprasidone vs Standard Therapy for Agitated Patients in the ED	Phase 4
Not yet recruiting	`NCT05974527` - Pilot Study 1: Efficacy and Safety of Sublingual Dexmedetomidine (BXCL501) for the Treatment of Agitation in the Emergency Department	Phase 4
Not yet recruiting	`NCT05522647` - Detection of Risk Behaviors: Pilot Observational Study With Bedridden and Agitated Patients.
Recruiting	`NCT02590744` - Effects of Preoperative Using of Eye Patches on Prevention of Emergence Agitation After Cataract Surgery	N/A
Recruiting	`NCT02164773` - Addition of Magnesium Sulfate to Caudal to Prevent Postoperative Emergence Agitation.	Phase 4
Completed	`NCT01524367` - Effect of Single-dose Dexmedetomidine on Emergence Excitement in Adults With Nasotracheal Intubation After Orthognathic Surgery	Phase 4
Completed	`NCT01501123` - Pre-hospital Agitation and Sedation Trial: A Randomized Controlled Trial of Haloperidol Versus Midazolam for the Sedation of the Agitated Patient	N/A
Completed	`NCT01021696` - Pain in Patients With Dementia and Behavioural Disturbances	Phase 2/Phase 3
Recruiting	`NCT05397639` - Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type	Phase 3
Terminated	`NCT03044249` - A Study of MP-101 in Dementia-Related Psychosis and/or Agitation and Aggression	Phase 2
Completed	`NCT05165914` - Midazolam Effect on Agitation Postnasal Surgery	N/A
Completed	`NCT04010305` - Sub-Lingual Dexmedetomidine in Agitation Associated With Schizophrenia	Phase 1
Completed	`NCT02720705` - Transbucal Dexmedetomidine for Prevention of Sevoflurane Emergence Agitation in Pre-school Children	Phase 2/Phase 3
Completed	`NCT02428283` - Scalp Nerve Block on Emergence Agitation	Phase 4
Completed	`NCT00457366` - A Comparison Study of the Efficacy of Quetiapine and Haloperidol in Agitated Adults in Emergency Room	Phase 4
Terminated	`NCT00315900` - Depakote Extended Release (ER) Versus Seroquel for Agitated Behaviors in Nursing Home Care Unit Patients With Dementia	Phase 3