A Study of MHE in Patients With Liver Diseases

Status Recruiting

Clinical Trial Summary

The investigators analyze the diagnostic efficacy of blood ammonia, neurophysiological/psychological tests and blood markers on MHE; to see the progression of HE under the condition of the drugs intervention and no drugs intervention in clinical real world.

Clinical Trial Description

In China, hepatic encephalopathy (HE) is a common complication and one of the most serious manifestations of liver disease, not only increasing the risks of death, but also seriously affecting the lives of the patients and their caregivers. CHE includes the 1st stage of HE and minimal encephalopathy (MHE). It has indicated in a study that the mortality rates of covert hepatic encephalopathy (CHE) and overt hepatic encephalopathy (OHE) were both high (21% and 21.8% respectively). At present, CHE, especially MHE, is not easy to diagnose in daily clinical work. This study aims to early diagnose MHE and find suitable treatment to benefit patients. The investigators analyze the diagnostic efficacy of blood ammonia, neurophysiological/psychological tests and blood markers on MHE; to see the progression of HE under the condition of the drugs intervention and no drugs intervention in clinical real world. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04058327
Study type	Observational
Source	Tongji Hospital
Contact	Qin Ning, MD., PhD.
Phone	+8602783662391
Email	qning@vip.sina.com
Status	Recruiting
Phase
Start date	May 1, 2019
Completion date	December 30, 2020

View Details

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