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CD19-CAR Immunotherapy for Childhood Acute Lymphoblastic Leukemia (ALL) — CD19TPALL  

Acute Lymphoblastic Leukemia Clinical Trial

Official title:
Immunotherapy With CD19ζ Gene-modified EBV-specific CTLs After Stem Cell Transplant in Children With High-risk Acute Lymphoblastic Leukaemia

Clinical Trial Summary

The aim of this clinical trial is to evaluate the feasibility, safety and biological effect of adoptive transfer of CD19ζ chimaeric receptor transduced donor-derived EBV-specific cytotoxic T-lymphocytes (EBV-CTL) in patients with high-risk or relapsed B cell precursor ALL after allogeneic Haematopoietic Stem Cell Transplantation (HSCT).

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01195480
Study type Interventional
Source University College, London
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date May 2012
Completion date November 2015
View Details
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