Acute Hyponatremia Clinical Trial
Official title:
Bipolar Versus Monopolar Resection of Benign Prostate Hyperplasia: A Comparison of the Effects on Plasma Electrolytes, Osmolarity and Hemoglobin
Aim of this prospective clinical study was to compare two different surgical techniques and
used solutions on serum electrolytes, bleeding and Transurethral Resection of Prostate
(TURP) syndrome undergoing TURP.
Fifty-three patients scheduled for elective TURP were enrolled in this prospective clinical
study. Patients were included one of two groups (Group Monopolar and Group Bipolar).
Background and Purpose:
Aim of this prospective clinical study was to compare two different surgical techniques and
used solutions on serum electrolytes, bleeding and Transurethral Resection of Prostate
(TURP) syndrome undergoing TURP.
Methods:
Fifty-three patients scheduled for elective TURP were enrolled in this prospective clinical
study. Patients were divided into two groups. Patients in Group M (Monopolar) (n=25) were
used monopolar resectoscope (Karl Storz, Tottling, Germany) and 5% mannitol as irrigating
solution. Patients in Group B (Bipolar) (n=25) were used bipolar resectoscope TURis
(OLYMPUS, Tokyo, Japan) and isotonic saline as irrigating solution. Patients who received
spinal anaesthesia were given 2.5-3 ml 0.5% hyperbaric bupivacain intrathecally and others
were given general anaesthesia. Patients demographics, prostate volumes, hemodynamic
parameters, volumes of irrigation and IV solutions were recorded. Blood samples were
collected preoperatively (control), 45 minutes after the induction (2nd Measurement) and 1
hour after the end of the operation for analyzing serum electrolytes, osmolarity, hemoglobin
values.
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment