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Acne Vulgaris clinical trials

View clinical trials related to Acne Vulgaris.

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NCT ID: NCT05089708 Completed - Acne Vulgaris Clinical Trials

AkLief Evaluation in Acne-induced Post-Inflammatory Hyperpigmentation

LEAP
Start date: December 22, 2021
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Trifarotene 50 microgram per gram (mcg/g) cream compared to its vehicle cream in the treatment of moderate acne vulgaris with risk of acne-induced post inflammatory hyperpigmentation (PIH) after 24 weeks of treatment in facial acne participants

NCT ID: NCT05071274 Completed - Acne Vulgaris Clinical Trials

A Proof of Concept Study to Evaluate the Efficacy and Tolerability of Microneedling With SkinPen in Female and Male Subjects With Facial Acne Vulgaris, Ages 18 Through 45

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

This single-center, proof of concept trial is being conducted over the course of 42 days followed by a 2-month post-last treatment visit in order to assess the efficacy and tolerability of the Sponsor's SkinPen device in treating Acne Vulgaris on the face.

NCT ID: NCT05012735 Completed - Acne Vulgaris Clinical Trials

A Study of a Hydrocolloid Bandage on Pimples

Start date: July 19, 2021
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the effectiveness and tolerability of a hydrocolloid bandage on pimples when used overnight for one week.

NCT ID: NCT05010538 Completed - Acne Vulgaris Clinical Trials

Sarecycline Truncal Acne Safety and Efficacy Response

TASER
Start date: March 9, 2021
Phase:
Study type: Observational

The purpose of this study is to determine the efficacy and safety of oral sarecycline 1.5 mg/kg/day in truncal acne. Patients with moderate to severe acne vulgaris will be observed over a period of 12 weeks. Lesion counts, investigator's global assessments, photography, and safety measures will be assessed for the trunk and face.

NCT ID: NCT04975412 Completed - Acne Vulgaris Clinical Trials

Relationship of Whole Blood Zinc Levels to Acne Severity

Start date: November 27, 2017
Phase:
Study type: Observational

Acne Vulgaris is one of the most common dermatologic diagnoses in the world. A number of studies have been conducted comparing serum zinc levels with acne vulgaris; however, no studies have yet been done in the Philippine setting. The objective of this study is to determine the relationship between whole blood zinc levels and the severity of acne vulgaris in Filipino patients and normal controls who are 18-25 years old.

NCT ID: NCT04960930 Completed - Acne Vulgaris Clinical Trials

To Evaluate the Efficacy and Safety of Minocycline Hydrochloride Foam in the Treatment of Moderate-to-severe Acne Vulgaris

Start date: September 17, 2021
Phase: Phase 3
Study type: Interventional

This is a randomized, multicenter, double-blind, vehicle-controlled, 2-arm study to evaluate the safety and efficacy in 12 weeks of FMX101 minocycline foam, 4%, compared to vehicle, in the treatment of subjects with moderate to severe facial acne vulgaris.

NCT ID: NCT04949932 Completed - Acne Vulgaris Clinical Trials

Application of Poly-herbal Powder for Treating Acne Vulgaris

Start date: April 3, 2021
Phase: N/A
Study type: Interventional

Acne is a common problem in adolescence to young adult. But there is no such remedy available for acne treatment which has no side effects. Different types of herbs powder has been using in patients with acne vulgaris in the traditional practice of Indian subcontinent as single form or compound. Scientific evidence have shown many herbs has no known side effects and effective on acne. These herbs have antibacterial, anti-inflammatory and anti-oxidant effects. So, This study is intended to find out an inexpensive and safe alternative by using some common herbs such as Azadirachta indica, Curcuma longa, Lens culinaris Mentha arvensis and Trigonella foenum-graecum. The aim of the study is to evaluate the clinical efficacy of Poly herbal powder (PHP) for treating patients with acne vulgaris. Total of 42 adults with acne vulgaris was recruited for this study. Study subjects was included both of male and female with age limit of 18 to 35 years. Duration of study is 05 months with "day one advertisement" for screening followed by randomization for the treatment. The duration of active participation of each study subject was 3 consecutive weeks or 21days. Difference of baseline and post intervention mean by Total lesion Count (TLC) compared with placebo and assesses the % of reduction of acne based on The Global Acne Grading System (GAGS) score. Safety assessment was obtained from the incidence and type of adverse events during study period.

NCT ID: NCT04943159 Completed - Acne Vulgaris Clinical Trials

Afamelanotide in Patients Suffering With Acne Vulgaris

Start date: August 24, 2010
Phase: Phase 2
Study type: Interventional

This study aims to evaluate the effect of afamelanotide on the facial inflammatory acne-related lesions in patients with mild to moderate acne vulgaris, including tolerability of afamelanotide by patients with moderate acne vulgaris and effects of the treatment on quality of life in eligible patients.

NCT ID: NCT04940767 Completed - Acne Vulgaris Clinical Trials

A Companion Treatment Study for Patients With Moderate to Severe Acne Vulgaris

Start date: June 28, 2021
Phase: Phase 4
Study type: Interventional

Acne vulgaris is a common disease of both males and females, usually manifesting initially during adolescence. The use of retinoic acid analogues such as adapalene, tazarotene and isotretinoin are also commonly prescribed to treat inflammation; dysregulated sebum production and comedonal acne. This study seeks to evaluate the efficacy and safety of concomitant use of both AMZEEQ® and oral isotretinoin compared to oral isotretinoin only use and to explore sequence dosing of both products as part of a long-term management protocol for acne vulgaris.

NCT ID: NCT04937374 Completed - Acne Vulgaris Clinical Trials

Efficacy and Tolerability of Rehmannia Glutinosa Leaf Extract in the Treatment of Acne Vulgaris

Start date: June 5, 2021
Phase: N/A
Study type: Interventional

In this study, The Investigator will be assessing the efficacy and tolerability of Rehmannia glutinosa Libosch leaf-based extract formulation consumption on the treatment of Acne Vulgaris in a randomized, double-blind, placebo-controlled study for the duration of 56 days.