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NCT00222391 Clinical Trial

Influence of Thoracic Epidural Anesthesia on Skin Sympathetic Activity and Heart Rate Variability

Abdominal Surgery Clinical Trial

Official title:
Influence of Thoracic Epidural Anesthesia on Skin Sympathetic Activity and Heart Rate Variability in Surgical Patients

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT00222391
Other study ID # 01-Anast-04
Secondary ID
Status Completed
Phase N/A
First received September 20, 2005
Last updated January 6, 2009
Start date April 2004
Est. completion date January 2006

Study information
Verified date March 2006
Source University Hospital Muenster
Contact n/a
Is FDA regulated No
Health authority Germany: Ethics Commission
Study type Observational

Clinical Trial Summary

The purpose of the study is to evaluate the impact of epidural anesthesia on sympathetic activity in surgical patients. The study investigates whether a segmental sympathetic block can be determined and can be correlated to level of the sensoric blockade.

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date January 2006
Est. primary completion date
Accepts healthy volunteers No
Gender Both
Age group 18 Years and older
Eligibility Inclusion Criteria:

- elective surgery

- combined anesthesia with thoracic epidural anesthesia 8 (Th6-9

- Body-mass-index < 30

Exclusion Criteria:

- Fever, Hypothermia, SIRS

- Microangiopathy

- Neuropathy

- Sensomotoric deficits

Study Design

Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Germany Department of Anesthesia and Intensive Care, University Hospital Muenster Muenster

Sponsors (1)
Lead Sponsor Collaborator
University Hospital Muenster

Country where clinical trial is conducted

Germany, 

References & Publications (1)

Freise H, Meissner A, Lauer S, Ellger B, Radke R, Bruewer M, Brodner G, Van Aken HK, Sielenkämper AW, Fischer LG. Thoracic epidural analgesia with low concentration of bupivacaine induces thoracic and lumbar sympathetic block: a randomized, double-blind c — View Citation

Outcome
Type Measure Description Time frame Safety issue
Primary Hemodynamic parameters
Secondary Level of sensoric block
Secondary skin temperature
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