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1st, 2nd or 3rd Recurrence of IDH Wild Type Glioblastoma Multiforme (GBM) clinical trials

View clinical trials related to 1st, 2nd or 3rd Recurrence of IDH Wild Type Glioblastoma Multiforme (GBM).

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NCT ID: NCT04782609 Not yet recruiting - Clinical trials for Glioblastoma Surgery

Study of Icapamespib (PU-AD) in Patients With Recurrent Malignant Glioma

Glio
Start date: April 2021
Phase: Phase 1
Study type: Interventional

This is a 2-part multicenter Phase 1b study designed to test icapamespib in patients with recurrent brain lesions. Part 1 of the trial will be a standard 3 by 3 dose escalation design where different doses are examined. Part 2 will be a dose expansion cohort to further evaluate the recommended Phase 2 dose (RP2D). The RP2D is defined as the dose level recommended for further clinical study, or the highest dose tested.