Uterine Cervical Dysplasia Clinical Trial
Official title:
Lidocaine Spray Compared With Submucosal Injection in Reducing Pain During Loop Electrosurgical Excision Procedure: a Randomized Controlled Trial
Loop Electrosurgical Excision Procedure (LEEP) is a widely used minor surgical procedure for
diagnosis and treatment of cervical intraepithelial neoplasia. During the procedure, several
methods have been proposed to reducing pain including submucosal block, paracervical block,
and oral analgesics. Submucosal (underneath the lining of the cervix) injection of lidocaine
appeared to be the most common methods used. However, from the investigators experience,
there is significant pain associated with the injection itself.
Lidocaine spray is an effective measure for pain control during minor gastrointestinal and
otolaryngological procedures. It is simple without pain related to application.
An objective of this study is to examine effectiveness of lidocaine spray versus lidocaine
submucosal injection by comparing pain scores at various stages of the LEEP procedure.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01014026 -
Self-sampling and Human Papillomavirus (HPV)-Testing for Unscreened Women in Cervical Cancer Prevention
|
Phase 3 | |
| Completed |
NCT00377845 -
Cervix Cytological Screening - Comparison of Tampon Self-Test and the Routine Smear.
|
Phase 0 | |
| Completed |
NCT02910388 -
LLETZ Under Direct Colposcopic Vision
|
N/A | |
| Completed |
NCT00596258 -
A Two-Stage Phase 2 Study Of A-007 Topical Gel in High-Grade Squamous Intraepithelial Lesions (HSIL)
|
Phase 2 | |
| Completed |
NCT03763565 -
Effectiveness of HPV Vaccine in Thai Adult Women
|
||
| Completed |
NCT04415840 -
Lugol's Solution in Addition to Acetic Acid During Colposcopy
|
||
| Recruiting |
NCT04783805 -
Conservative Management of HSIL in Patients With Future Pregnancy Aspiration
|
||
| Completed |
NCT04326049 -
LLETZ With Videocolposcopy Versus LLETZ With Binocular Colposcopy
|
N/A | |
| Completed |
NCT02486471 -
Hemostatic Procedure After Biopsy of the Cervix
|
N/A | |
| Completed |
NCT02515162 -
Fischer Cone Biopsy Excisor Versus Loop Excision Procedure for Conization
|
N/A | |
| Completed |
NCT01405768 -
Buffered Lidocaine for Loop Electrosurgical Excision Procedures (LEEPs)
|
Phase 2 | |
| Completed |
NCT00264732 -
A Study of Amolimogene (ZYC101a) in Patients With High Grade Cervical Intraepithelial Lesions of the Uterine Cervix
|
Phase 2/Phase 3 | |
| Completed |
NCT03296566 -
The SAFE Study: Satisfaction and Adherence to Follow-Up With Colposcopy Exams
|
N/A | |
| Completed |
NCT02346227 -
Impact of AV2 Antiviral Drug on the Treatment of HPV-associated Lesions of the Uterine Cervix
|
Phase 3 | |
| Completed |
NCT02330471 -
Forced Versus Spray Coagulation in Women Undergoing LLETZ-conization for Cervical Dysplasia: a Randomized Trial
|
Phase 3 | |
| Completed |
NCT01035580 -
Trial on Safety and Pharmacokinetics of Intravaginal Curcumin
|
Phase 1 | |
| Completed |
NCT01639820 -
Comparison of Pelvic Lymphadenectomy Versus Isolated Sentinel Lymph Node Biopsy Procedure for Early Stages of Cervical Cancers : a Multicenter Study With Evaluation of Medico-economic Impacts
|
N/A | |
| Completed |
NCT00285207 -
Safety and Efficacy of A-007 Topical Gel in the Treatment of High-Grade Squamous Intraepithelial Lesions (HSIL) of the Cervix
|
Phase 2 | |
| Recruiting |
NCT05225493 -
HIV Indicator Diseases in Hospital and Primary Care
|
||
| Completed |
NCT01034358 -
Immune Response to the Human Papillomavirus Vaccine in Young Women With Inflammatory Bowel Disease
|
Phase 4 |