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Brief Escalation of Adalimumab Treatment for Prevention of Clinical Relapse in IBD — BEAT-IBD  

Ulcerative Colitis Clinical Trial

Official title:
Brief Escalation of Adalimumab Treatment for Prevention of Clinical Relapse in IBD

Clinical Trial Summary

To examine whether a temporary three month increase in adalimumab dosing will prevent relapse in patients with inflammatory bowel disease in clinical remission who have elevated calprotectin.

Clinical Trial Description

Patients using adalimumab for Crohn's disease or ulcerative colitis who are in clinical remission will be followed with fecal calprotectin monitoring every 3 months. Patients with a sustained rise in calprotectin who maintain clinical remission will be offered an opportunity to have an increase in adalimumab for three months. Patients who use the three months of increased adalimumab dosing will be compared to patients who do not use increased dosing to determine if relapse rates differ between these two groups. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03059849
Study type Interventional
Source McMaster University
Contact
Status Withdrawn
Phase Phase 4
Start date February 1, 2018
Completion date September 1, 2019
View Details
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