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Clinical Trial Summary

Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T1D). In a preventive setting, in T1D patients still free of complications, the research of non-pharmacological interventions to improve endothelial function appears fundamental. In this randomized controlled trial, the effects of exercise training on endothelial function will be evaluated in T1D adults. Secondary objectives are to evaluate the exercise training effects on the micro and macrovascular function and exercise-induced tissue vasoreactivity and their possible neurometabolic consequences. An improvement in vascular function, particularly endothelium-dependent, as well as in neurometabolic profile, through this non-pharmacological strategy is expected


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03528226
Study type Interventional
Source University Hospital, Lille
Contact Pierre Fontaine, MD,PhD
Phone 320445843
Email pierre.fontaine@chru-lille.fr
Status Recruiting
Phase N/A
Start date November 12, 2019
Completion date March 2025

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