Type 2 Diabetes Mellitus Clinical Trial
Official title:
A Single Arm Feasibility Study of GlycoLeap, an On-line Lifestyle Modification and Self-management Program for People With Type 2 Diabetes
This single arm pilot study will explore the feasibility of GlycoLeap, a proprietary online lifestyle modification and self-management education program developed in Singapore for people with type 2 diabetes, as an add-on to primary care delivered through one of the SingHealth Polyclinics.
Lifestyle modification - focusing on a healthy diet, regular exercise and behaviour change -
are the mainstay of first-line therapies in managing diabetes. There is strong evidence that
lifestyle interventions can result in modest weight loss and improvements in clinical metrics
such as glycated haemoglobin (HbA1c), blood pressure and cholesterol. For people with type 2
diabetes, lifestyle modification and self-management education can lead to improved clinical
outcomes and reduced risks of complications.
Operationally, such interventions are often difficult to administer in the primary care and
community setting because of lack of provider time/resources/training and difficulty in
engaging patients. Fortunately, there is a growing body of evidence which shows that online
programs and smartphone-based interventions can lead to improved clinical outcomes like
weight loss and HbA1c reduction. Moreover, these interventions can be disseminated to a
larger group of people and at a low cost. However, results from community based studies often
fail to live up to what is achieved in clinical trials due to lack of clinician oversight and
support. Without this support, patients often fail to engage in the intervention to the
levels required for health benefits to materialize.
This feasibility study will explore the use of GlycoLeap, a proprietary online lifestyle
modification and self-management education program developed in Singapore for people with
type 2 diabetes, as an add-on to primary care delivered through one of the SingHealth
Polyclinics. The goal of the study is to test whether patients with diabetes who receive care
at the clinic are amenable to such an intervention, to quantify program fidelity for those
who do enroll in the study, and to explore the extent to which the intervention can be used
in conjunction with primary care in efforts to improve health outcomes.
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