Postoperative Analgesia in Patients With Microvascular Decompression

Trigeminal Neuralgia Clinical Trial

Official title: Efficacy and Safety of Multimodal Analgesia Used in Patients With Microvascular Decompression

Status Active, not recruiting

Clinical Trial Summary

Perioperative pain is caused by a variety of harmful factors through multiple mechanisms, therefore, reasonable postoperative analgesia should be combined with drugs or measures of different mechanism , which is called multimodal analgesia. Multimodal analgesia could minimize side effects and achieve a better analgesic effect. Commonly used strategies of multimodal analgesia are oral analgesic drug, nerve block, patient controlled analgesia and so on. This study will observe the effect of multimodal analgesia on postoperative pain in patients with microvascular decompression and record side effects. Finally, it will provide technical support for the guidance of postoperative analgesia in patients of trigeminal neuralgia.

Clinical Trial Description

The investigators will collect 90 cases which will be divided into 3 groups. Patients in Group A will receive scalp nerve block and patient-controlled analgesia which contains sufentanil and ondansetron. In Group B, patient-controlled analgesia which contains sufentanil, ondansetron and ketamine will be applied. In Group C, patient-controlled analgesia which contains sufentanil and ondansetron will be applied. ;

Related Conditions & MeSH terms

• Neuralgia
• Trigeminal Neuralgia

• NCT number: NCT03152955
• Study type: Interventional
• Source: Xiangya Hospital of Central South University
• Status: Active, not recruiting
• Phase: Phase 4
• Start date: May 15, 2017
• Completion date: May 15, 2018