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Offsetting Hippocampal Degeneration in m-sTBI — m-sTBI  

Traumatic Brain Injury Clinical Trial

Official title:
Offsetting Hippocampal Degeneration in Moderate to Severe TBI

Clinical Trial Summary

The goal of this study is to establish the feasibility of an intervention designed to improve memory in patients who have experienced a moderate or severe traumatic brain injury (m-sTBI) and to examine its effect on brain structures.

Clinical Trial Description

The purpose of this study is to establish the feasibility of a novel intervention, and explore biomarker predictors of neurodegeneration and response to the proposed intervention. This 16 week intervention utilises allocentric spatial navigation tasks to improve memory and counteract hippocampal neurodegeneration. This intervention will be administered in combination with neuropsychological assessments, MR imaging, and the analysis of genomic variants at two time points; 7 months post-TBI and 12 months post-TBI. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03727334
Study type Interventional
Source University of British Columbia
Contact Nishtha Parag, BSc
Phone 604-418-4160
Email nishthap@psych.ubc.ca
Status Recruiting
Phase N/A
Start date July 25, 2019
Completion date July 2024
View Details
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