Tetralogy of Fallot Clinical Trial
Official title:
Effects of Changes in Fluid Status on Right Ventricular Volumes and Function
The purpose of this study is to evaluate the correlation between fluid volume status and right ventricular volume and function, in those with free pulmonary valve insufficiency after Tetralogy of Fallot (TOF) repair.
The purpose of this study is to measure the changes in Right Ventricular size and function with changes in preload, using cardiovascular magnetic resonance (CMR). Based on an intensive research and clinical observations the investigators hypothesize that changes in volume status cause a statistically significant difference in the Cardiovascular magnetic resonance (CMR) measured RV End Diastolic Volume (EDV), end-systolic volume (ESV), ejection fraction (EF) and pulmonary regurgitation (PR). The investigator hypothesizes that smaller changes will occur in left ventricular LV EDV, ESV, and EF. 1. To establish a correlation between the changes in preload volume status and RV size and function in patients with free pulmonary insufficiency (PI) after TOF repair using CMRI. 2. To assess the effects of preload status on the measured severity of pulmonary regurgitation (PR). 3. To assess the effects of preload status on the left ventricular (LV) size This study will be conducted in compliance with this protocol, good clinical practice and the applicable regulatory requirements. ;
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