Personality Disorders and Substance Use Disorders in a Sexual Context in the Man Having Sex With Other Men Population

Substance Use Disorders Clinical Trial

— PSYCHEMS  

Official title:

A Study of the Relationship Between Personality Disorders and Substance Use Disorders in a Sexual Context in the Man Having Sex With Other Men Population - An Observational Study Based on a Cross-sectional Survey.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03753737
• Other study ID #: 69HCL18_0509
• Secondary ID: 2018-A02168-47
• Status: Completed
• Start date: November 22, 2018
• Est. completion date: April 29, 2019

Study information

• Verified date: May 2019
• Source: Hospices Civils de Lyon
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Chemsex refers to the use of psychoactive drugs in a sexual context, mainly cathinones, GHB/GBL, methamphetamine, cocaine and ketamine. This can cause infectious or psychiatric complications, addictions, and often goes with high risk sexual behaviours. Recent studies have highlighted the relationship between personality disorders, substance use disorders and risky sexual behaviours. It is important to understand the factors associated with chemsex in order to offer adapted prevention and care plans.

The study hypothesis is that personality disorders, evaluated with the PDQ-4+ questionnaire, are more frequent among man having sex with other men with a substance use disorder linked to chemsex than among man having sex with other men who have never practised chemsex.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 94
• Est. completion date: April 29, 2019
• Est. primary completion date: April 29, 2019
• Accepts healthy volunteers: No
• Gender: Male
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Age over 18

• Men who have Sex with Men

• No opposition to participate to the study

• Chemsex group: to attend an addiction care center for past or present mild, moderate or severe substance-related disorder(s) according to DSM-V criteria, occurring in a sexual context and concerning cathinones, GHB/GBL, methamphetamine, cocaine and/or ketamine.

• Control group: to consult for a PrEP prescription and never have used cathinones, GHB/GBL, methamphetamine, cocaine or ketamine before or during sex.

Exclusion Criteria:

• Deprivation of liberty

• Guardianship

• Chemsex group: simple experience of chemsex without substance use disorder

Related Conditions & MeSH terms

• Disease
• Personality Disorders
• Substance Use Disorders
• Substance-Related Disorders

Intervention

Other:
• Questionnaires and semi-structured interview
Questionnaires : PDQ-4+ (personality disorders), HAD (Anxiety and Depression), AUDIT-c (Alcohol consumption), CTQ-SF (Childhood Trauma Questionnaire). Semi-structured interview : Evaluation of socio-demographic characteristics, psychiatric and addiction comorbidities, sexually transmitted infections, sexual practices, sexual dysfunction, hypersexual disorder.

Locations

Country	Name	City	State
France	CSAPA - Service Hépato-gastroentérologie	Lyon

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Personality disorders	Positive score for 1 or more DSM-V personality disorders(PD) using French version of the PDQ4+,Personality Diagnostic Questionnaire-Version4,comprising: Combined score of overall personality disturbance (ranges0 to 93);higher values reflect a more important personality disturbance; Borderline PD:Score Ranges(SR) 0 to 9,positive(+) if = 5; Narcissistic PD:SR 0 to 9,+ if =5; Histrionic PD:SR 0 to 8,+ if =5; Antisocial PD:SR 0 to 8,+ if =4 and criteria 99 positive; Avoidant PD:SR 0 to 7,+ if =4; Dependent PD:SR 0 to 8,+ if =5; Obsessive-Compulsive PD:SR 0 to 8,+ if =4; Paranoid PD:SR 0 to 7,+ if =4; Schizoid PD:SR 0 to 7,+ if =4; Schizotypal PD:SR 0 to 9,+ if =5; Questionnaire must be interpreted with caution if 1 of the 2 "Suspect Questionnaire" items is +, or if at least 2 of the 4 "Too Good" items are +; Negativistic and depressive PD are evaluated with the PDQ4+ but are not part of the outcome measures in the study	1 day