Stroke Clinical Trial
Official title:
The Acute and Chronic Effects of Heel Raises on Central Blood Pressures, Arterial Compliance and Cerebral and Peripheral Oxygen Perfusion After Stroke
NCT number | NCT03423433 |
Other study ID # | RKE_2017_002 |
Secondary ID | |
Status | Completed |
Phase | N/A |
First received | |
Last updated | |
Start date | June 1, 2018 |
Est. completion date | May 1, 2019 |
Verified date | January 2020 |
Source | University of Winchester |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Physical inactivity and increased sedentary time are linked to increased blood pressure and
may cause decreases in peripheral and cerebral oxygen perfusion in stroke survivors.
Nonetheless, stroke survivors are significantly less active than their healthy counterparts
due to physical incapability or a lack of confidence in physical capability. This study will
determine whether a simple and non-demanding movement such as repeated heel raises are able
to cause acute and chronic decreases in peripheral and central blood pressure and increases
in oxygen perfusion and cognitive performance.
Thirty participants will be recruited to this study. All will take part in four sessions. One
familiarisation session will acclimatise participants to the equipment used involving central
and peripheral blood pressures, pulse wave velocity, arterial stiffness, maximal voluntary
contractions of the medial gastrocnemius and Stroop tasks.. Two experimental sessions will
take place involving extended sedentary time (one involving uninterrupted sedentary time and
one including ten heel raises every ten minutes). A control condition of 15 participants will
then be tested ten weeks post-. The experimental condition of 15 participants will undergo a
ten-week heel raise prescribed programme before having peripheral and central blood pressure,
pulse wave velocity, arterial stiffness, peripheral and cerebral oxygen perfusion, cognitive
performance and maximal voluntary contraction of the medial gastrocnemius assessed after
their programme.
Status | Completed |
Enrollment | 15 |
Est. completion date | May 1, 2019 |
Est. primary completion date | May 1, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Have experienced a stroke in the past ten years - Physically capable of heel raise motion Exclusion Criteria: - Diabetics - Inability to perform heel raise motion |
Country | Name | City | State |
---|---|---|---|
United Kingdom | University of Winchester | Winchester | Hampshire |
Lead Sponsor | Collaborator |
---|---|
University of Winchester |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Central and peripheral blood pressure | Acute and chronic changes to central and peripheral blood pressures due to heel raises | After three data collection sessions (within 2 weeks) and 10 weeks- post | |
Secondary | Pulse wave velocity | Acute and chronic changes to carotid-femoral pulse wave velocity due to heel raises | After three data collection sessions (within 2 weeks) and 10 weeks- post | |
Secondary | Cerebral perfusion | Acute and chronic changes to cerebral perfusion (Near infra-red spectroscopy) due to heel raises | After three data collection sessions (within 2 weeks) and 10 weeks- post | |
Secondary | Cognitive performance | Stroop task performance due to heel raises | After three data collection sessions (within 2 weeks) and 10 weeks- post |
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