Stroke Clinical Trial
Official title:
Recovery of Impairments Early After Stroke
Upper limb recovery after stroke is highly predictable early after stroke. Nijland et al.
showed that based on two simple clinical bedside tests - 'Shoulder Abduction' and 'Finger
Extension' (the so called 'SAFE model' [Stinear et al., 2012]) - measured within the first 72
hours after stroke, ~87% of the patients could be correctly classified as either regaining or
not regaining some dexterity (recoverers or nonrecoverers, respectively) (Nijland et al.,
2010). This kind of information regarding the patients' functional prognosis allows proper
discharge planning, setting realistic rehabilitation goals, and adequate patient information.
However, the length of hospital stay after stroke has been decreasing. Therefore, knowledge
is needed regarding the ability to make an accurate first prediction within the first 24
hours after stroke onset while using simple clinical bedside assessments. This would
facilitate an earlier triage and with that, an accelerated and smooth transition of patients
within the stroke care continuum. In addition, a first prediction within 24 hours poststroke
has the potential to decrease health care expenses, as length of hospital stay after an acute
stroke is ~30% of the total costs (i.e., direct and indirect costs) associated with stroke
(Roger et al., 2012; Fattore et al., 2012).
The primary objective of aRISE is to determine the ability of the behavioral biometric
impairments 'Shoulder Abduction' and 'Finger Extension' measured <24 hours poststroke to
predict outcome of upper limb capacity 3 months after stroke. The secondary aim is to
investigate the the added value of other simple clinical bedside tests for predicting outcome
of upper limb capacity 3 months poststroke.
aRISE is a prospective longitudinal observational cohort study of 40 first-ever ischemic
stroke patients, who will be assessed <24 hours, 7 days and 3 months after stroke onset.
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