Stroke Cincinnati Prehospital Stroke Severity Scale Evaluation iN prEhospital

Stroke Clinical Trial

— SCENE  

Official title:

Evaluation of the Performances of the Cincinnati Prehospital Stroke Severity Scale Realized During Telephone Call With Emergency Department Physicians to Predict Large-vessel Occlusion

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03181412
• Other study ID #: 69HCL17_0146
• Status: Completed
• Start date: June 25, 2018
• Est. completion date: January 31, 2022

Study information

• Verified date: November 2022
• Source: Hospices Civils de Lyon
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The effectiveness of acute ischemic stroke (AIS) management has improved considerably in recent years with thrombolysis and more recently with mechanical thrombectomy (MT). Currently, mechanical thrombectomy can only be performed in stroke unit with an interventional neuroradiology center by experienced/qualified interventional neuroradiologists. In the Rhone area, only one hospital has the authorization to perform mechanical thrombectomy. Therefore, transferring directly eligible acute ischemic stroke patients for mechanical thrombectomy to this center constitutes an important stake of the triage of suspected acute ischemic stroke patients. Some validated scores for the identification of severe strokes and large vessel occlusion, including the Cincinnati prehospital stroke severity scale (CPSSS), appear to be relevant for pre-hospital use in order to identify patients potentially eligible for mechanical thrombectomy and address them to a stoke unit with interventional radiology center.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1272
• Est. completion date: January 31, 2022
• Est. primary completion date: January 31, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Consecutive patients calling emergency medical services for suspected acute ischemic stroke

Exclusion Criteria:

• Symptom onset (or the last time the patient was seen without deficit ) of more than 6 hours

Related Conditions & MeSH terms

• Stroke

Intervention

Diagnostic Test:
• Questionnaire
Tests from Cincinnati prehospital stroke severity scale (CPSSS) will be carried out by the physician at emergency medical services on telephone call with firemen, paramedics or the emergency medical services team for any stroke suspicion that meets the criteria for inclusion. Emergency department physician will have to follow a standardized questionnaire to complete the different items of the score. The score will not be calculated by emergency department physician and will not influence the orientation and management of patients. The final diagnosis will be the presence or absence of a large vessel occlusion. This diagnosis will be done on cerebral imaging by a neurologist.

Locations

Country	Name	City	State
France	Neurologie, Hôpital Neurologique - HCL	Bron
France	Médecine d'urgence, Clinique de la Sauvegarde	Lyon
France	Médecine d'urgence, Hôpital de la Croix-Rousse - HCL	Lyon
France	Médecine d'urgence, Hôpital Desgenettes	Lyon
France	Médecine d'urgence, Hôpital Mutualiste Médipôle	Lyon
France	Médecine d'urgence, Hôpital Saint Joseph Saint Luc	Lyon
France	SAMU 69 , Hôpital Edouard Herriot	Lyon
France	Urgentiste, Centre Hospitalier Lyon Sud	Pierre-Bénite
France	Médecine d'urgence, CH de Roanne	Roanne
France	Médecine d'urgence, Hôpital Nord-Ouest	Tarare
France	Services Médecine d'urgence et Neurologie, CH de Vienne	Vienne
France	Services Neurologie et Médecine d'urgence, CH de Villefranche sur Saône	Villefranche-sur-Saône

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Performances of Cincinnati prehospital stroke severity scale	The Cincinnati prehospital stroke severity scale is composed of 3 items: 2 points if the patient has a deviation of the gaze, 1 point if the patient is not able to give the date and answer to a simple order such as closing the eyes or clenching the fist and 1 point if the patient presents a hemiplegia. The CPSSS score ranges from 0 to 4, highest value indicating the worst score. It will be considered positive if it is equal to 2 or more.; Performances will be evaluated in terms of sensitivity, specificity, positive and negative predictive values.	1 day