Clinical Trials Logo
NCT number NCT02822144
Study type Interventional
Source Rennes University Hospital
Contact Claire FOUGEROU, PharmD
Phone 033299283753
Email claire.fougerou@chu-rennes.fr
Status Recruiting
Phase Phase 3
Start date September 29, 2016
Completion date December 2019

Clinical Trial Summary

In France, the annual incidence rate of acute ischaemic stroke is around 150 000 patients, 65 % of whom keep long-term disability. Several multicentric randomized controlled trials have shown the benefit of a mechanical thrombectomy in the acute phase of ischaemic stroke on functional disability, compared to a medical treatment alone (thrombolysis).

The timeliness of revascularisation is an essential factor of good prognosis. This intra-arterial treatment, associated with thrombolysis if applicable, is the reference treatment of large-vessel occlusion. The stillness of the patient is required to control the safety of the recanalization. Currently, either a general anesthesia or a sedation can be performed.

Several studies have shown a trend to superiority of the sedation but none was conducted with a high level of proof methodology.

The aim of our multicentric randomized controlled trial is to compare sedation and general anesthesia during intra-arterial thrombectomy for an acute ischaemic stroke in the anterior cerebral circulation. The main outcome will be the efficacy on the functional neurological prognosis at 3 months.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


See also
  Status Clinical Trial Phase
Completed NCT00391378 - Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS) N/A
Completed NCT01662960 - Visual Feedback Therapy for Treating Individuals With Hemiparesis Following Stroke N/A
Recruiting NCT03281590 - Stroke and Cerebrovascular Diseases Registry N/A
Not yet recruiting NCT03287739 - Recovery of Impairments Early After Stroke N/A
Recruiting NCT03305731 - Activating Behavior for Lasting Engagement After Stroke N/A
Not yet recruiting NCT03294187 - Encouragement-induced Movement Therapy in Daily Life Phase 2
Recruiting NCT02513589 - Molecular Imaging of Inflammation With 18F-PBR06 to Identify Unstable Carotid Plaques in Patients With Stroke Phase 2
Recruiting NCT02577276 - Evaluation of a Tele-Rehabilitation Service Program N/A
Not yet recruiting NCT03177954 - Developing a Patient Oriented Discharge Summary for Stroke Inpatients N/A
Not yet recruiting NCT03259932 - Comparison of Fatigue and Recovery After Stroke Depending on the Usual Management With or Without Physical Training N/A
Not yet recruiting NCT03274505 - Sleep Disorders in Transient Ischemic Attack and Stroke: SOMN'AIC Study N/A
Not yet recruiting NCT03298243 - Use of Sensory Substitution to Improve Arm Control After Stroke N/A
Recruiting NCT03080454 - The Role of Trans-spinal Direct Current Stimulation (tsDCS) in Treating Patients With Hand Spasticity After Stroke N/A
Recruiting NCT02828306 - Computer Based Algorithm for Patient Specific Implants for Cranioplasty in Patients With Skull Defects N/A
Recruiting NCT02889562 - Apixaban Versus Warfarin for the Management of Post-operative Atrial Fibrillation Phase 2/Phase 3
Recruiting NCT02906956 - Music and Adherence Home Programs Post Stroke Phase 0
Recruiting NCT03025776 - One vs. Two Hand Use After Stroke: Role of Task Requirements N/A
Recruiting NCT02917213 - Imaging Silent Brain Infarct And Thrombosis in Acute Myocardial Infarction N/A
Recruiting NCT02916030 - Vitamin D and Stroke N/A
Active, not recruiting NCT02753257 - Validation of Sensitivity and Specificity of a Multi-Omic Precision Diagnostic for Acute Stroke Evaluation N/A