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NCT number NCT02513589
Study type Interventional
Source University Hospital, Bordeaux
Contact Paolo ZANOTTI-FREGONARA
Phone 0556623126
Email paolo.zanotti-fregonara@chu-bordeaux.fr
Status Recruiting
Phase Phase 2
Start date September 18, 2017
Completion date January 2019

Clinical Trial Summary

Evaluating an innovative molecular imaging technique to visualize inflammation of the atherosclerotic plaque in patients with a recent ischemic stroke (<15 days) with carotid stenosis> 50%, by performing a Positron emission tomography-computed tomography (PET-CT) with PBR06 18F, a tracer for Translocator protein (TPSO).


Clinical Trial Description

More than one third of cerebral ischemic events are related to an atheromatous plaque. Inflammation, through a key player, the macrophage, is associated with increased metabolic activity of atherosclerotic plaque and its possible rupture. Inflammation within the plate is thus a marker of instability. These data underscore the importance of a prospective evaluation of inflammation with specific imaging with PET tracers inflammation.


Study Design


Related Conditions & MeSH terms


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