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Stroke clinical trials

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NCT ID: NCT04339699 Suspended - Stroke, Ischemic Clinical Trials

NobleStitch EL STITCH Trial is a PFO Comparative Trial

STITCH
Start date: January 1, 2021
Phase: N/A
Study type: Interventional

STITCH - Prospective Multi-Center Comparative Parallel Concurrent Study of the NobleStitchâ„¢ EL versus FDA-approved Amplatzer Occluder device for closure of Patent Foramen Ovale to prevent recurrent Ischemic stroke.

NCT ID: NCT04290988 Suspended - Stroke Clinical Trials

Circuitry Assessment and Reinforcement Training Effects on Recovery

CARTER
Start date: September 23, 2020
Phase: N/A
Study type: Interventional

This study investigates if electroencephalography (EEG) neurofeedback training is more beneficial than sham feedback training for the improvement of communication, anxiety, and sleep quality in individuals with aphasia. Half of the participants will receive active EEG neurofeedback sessions first, followed by sham feedback sessions in a crossover design. The other half of participants will undergo sham feedback sessions first, followed by active neurofeedback.

NCT ID: NCT04288960 Suspended - Stroke Clinical Trials

Validity of a Belt Mounted Accelerometer to Assess Walking Measures in Patients With Chronic Stroke

Start date: September 1, 2022
Phase:
Study type: Observational

The aim of this study is to validate the G-walk for several gait parameters, tested against a gold standard three dimensional camera system. This research will inform researchers and practitioners as to whether the G-Walk is a suitable and valid tool to easily assess walking ability in people with chronic stroke.

NCT ID: NCT04062539 Suspended - Stroke Clinical Trials

Total Cerebral Protection With Embolic Protection Devices Thoracic Aortic Stenting

Start date: October 4, 2018
Phase:
Study type: Observational

Stroke and silent cerebral infarction are a real risk with thoracic enodvascular aortic repair (TEVAR). The investigator propose to prospectively observational study with enrolment of all patients undergoing TEVAR for thoracic and thoracoabdominal conditions including aneurysmal degeneration, Type B dissection and acute aortic syndromes over a 24 month period, equating to a minimum of 20-30 patients per year. Patients undergoing juxtra-renal and infra-renal aortic stenting will form a control group.

NCT ID: NCT04048668 Suspended - Stroke, Acute Clinical Trials

tDCS to Treat Subacute Aphasia

Start date: September 1, 2019
Phase: N/A
Study type: Interventional

This study proposes to use transcranial direct current stimulation (tDCS), a technique by which a very small electrical current (2 mA) is applied to the scalp, along side speech therapy in patients with subacute stroke and aphasia in order to enhance language recovery. Aphasic patients in an inpatient neurorehabilitation facility who have experienced a stroke between one week and three months prior to enrollment will be invited to participate. Participants will receive either real or sham tDCS to the left hemisphere of the brain for a minimum of 5 consecutive sessions to up-to a max of 10 sessions depending on the length of their rehab stay . Stimulation will be paired with with the patient's normal speech therapy schedule. Participant's language skills will be assessed at baseline and immediately after the last session of therapy in order to determine whether tDCS is associated with either transient or persistent improvement in language.

NCT ID: NCT04038424 Suspended - Clinical trials for Ischemic Stroke and Hemorrhagic Stroke

The Effect of Art Therapy on Patients With Stroke

Start date: September 20, 2019
Phase: N/A
Study type: Interventional

Stroke can affect the physical, emotional and social aspects of the patient and their family members. It is the main cause of complex disability, with a high number of people living with its effects. Stroke can result in impairments in motor function, language, cognition, sensory processing, cognition, and emotional disturbances, which can affect the performance of functional activities and mental health status. Getting patients involved in art therapy (AT) class has shown to alleviate stress and promote a sense of wellbeing, which can aid their recovery and rehabilitation. The benefits of art therapy for people living with different health conditions worldwide have been reported, however, its effect on Egyptian patients with stroke has been neglected.

NCT ID: NCT04007315 Suspended - Stroke Clinical Trials

SaeboGlove Therapy for Severe Upper Limb Disability and Severe Hand Impairment After Stroke

SUSHI
Start date: November 21, 2019
Phase: N/A
Study type: Interventional

The study will aim to determine whether 6-weeks of using a SaeboGlove independently (with or without help from a carer) improves upper limb function (measured using the Action Research Arm Test score) in comparison to usual care alone in people with reduced active finger extension, severe upper limb disability and severe hand impairment after recent stroke.

NCT ID: NCT03869138 Suspended - Stroke Clinical Trials

Alternative Therapies for Improving Physical Function in Individuals With Stroke

Start date: September 9, 2019
Phase: N/A
Study type: Interventional

Neurological impairment is a devastating disease for patients and their families and a leading cause of adult disability. Traditional rehabilitative therapies can help regain motor function and ameliorate disability. However, health care reimbursed rehabilitation is usually provided for up to 6 months post stroke (3 months in form of inpatient therapy and 3 months in outpatient therapy). There are increasing community and other facilities offering rehabilitation in form of conventional, recreational and alternative (Yoga, Tai-chi) therapy. However, implementation of these conventional therapy techniques in individuals with neurological disorder impairments is tedious, resource-intensive, and costly, often requiring transportation of patients to specialized facilities. Based on recent evidence suggesting significant benefits of repetitive, task-orientated training, investigators propose to evaluate the feasibility of an alternative dance and gaming based virtual dance and gaming based therapy to improve overall physical function of community-dwelling individuals with neurological impairments, compared to conventional therapeutic rehabilitation. This pilot study aims to systematically obtain pilot data on compliance and efficacy as well as performing power analysis and sample size calculation for developing it into a randomized controlled trial for extramural funding purposes. The objective of the study is to determine the safety, feasibility, compliance and efficacy of an alternative dance and gaming-based virtual gaming therapy to improve overall physical function of community-dwelling individuals with neurologically impairment and compare it to that of conventional rehabilitation and also to determine the gains in community participation and integration with longer-term compliance to the dance and gaming -based intervention.

NCT ID: NCT03641963 Suspended - Stroke, Acute Clinical Trials

aICP Measurement in Patients With Cerebral Artery Infarction / aICP MCA Infarction

aICPStroke
Start date: December 1, 2018
Phase: N/A
Study type: Interventional

Space-occupying, malignant middle cerebral artery (M-MCA) infarctions are still one of the most devastating forms of ischemic stroke, with a mortality of up to 80% in untreated patients. It is reported that early hemicraniectomy leads to a substantial decrease in mortality at 6 and 12 months and is likely to improve functional outcome. Thus, this study investigates if non-invasive intracranial pressure (ICP) measuring could represent an objective value to determine the time point to indicate decompressive craniectomy surgery. However, there are still important questions about the individual indication for decompressive surgery. In consideration of a variable clinical course (some patients develop fatal brain edema early, whereas other patients do not show severe brain swelling for several days), achieving a way to measure, control and predict malignant brain edema formation would be of extremely important value.

NCT ID: NCT03163459 Suspended - Stroke, Acute Clinical Trials

Short-duration Selective Brain Cooling for Patients Undergoing Mechanical Thrombectomy

Start date: February 6, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

To determine the efficacy and safety of short-duration intra-artery selective brain cooling in addition to mechanical thrombectomy in patients with acute ischemic stroke.