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Intensive Ambulance-delivered Blood Pressure Reduction in Hyper-Acute Stroke Trial — INTERACT4  

Stroke, Acute Clinical Trial

Official title:
Intensive Ambulance-delivered Blood Pressure Reduction in Hyper-Acute Stroke Trial

Clinical Trial Summary

A multicentre, ambulance-delivered, prospective, randomized, open-label, blinded endpoint (PROBE) study to assess the effects of hyperacute intensive blood pressure (BP) lowering initiated in ambulance setting on (i) functional outcome in patients with acute stroke (ii) safety in patients with confirmed acute stroke and other conditions that were initially suspected as acute stroke (i.e. stroke mimic).

Clinical Trial Description

As an investigator initiated and conducted, multicentre, ambulance-delivered, prospective, randomised, open-label, blinded outcome (PROBE) study. INTERACT4 aims to evaluate the effects of functional outcome according to an ordinal analysis of the full range of scores on the mRS, the safety in all randomised patients; reperfusion treatment (thrombolysis and/or thrombectomy) related symptomatic ICH (sICH, according to standard definitions), infarct size, the time to and overall rate of reperfusion treatment in AIS patients; hematoma volume and early expansion in ICH. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03790800
Study type Interventional
Source The George Institute for Global Health, China
Contact
Status Completed
Phase Phase 3
Start date March 20, 2020
Completion date November 30, 2023
View Details
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