Pain Clinical Trial
Official title:
Evaluation Of The Analgesia Nociception Index vs. Surgical Pleth Index Under General And Regional Anaesthesia And The Effect Of Posture. A Prospective Randomized Controlled Trial.
There is a lack of sufficient analgesia monitoring apart from surrogate parameters. The analgesia nociception index (ANI) shall be evaluated under general and regional anaesthesia.
While sophisticated haemodynamic monitoring as well as depth of neuromuscular block and
sedation are established in daily clinical routine monitoring of analgesia remains poorly
represented. The surgical pleth index (SPI) algorithm takes into account both central and
peripheral sympathetic tone via the normalised heart beat interval and the plethysmographic
pulse wave amplitude and has been described before. A more detailed investigation on the SPI
and its behaviour under a posture maneuver shows the limitation of the device.
Another device developed calculates the "analgesia nociception index" (ANI) by heart rate
variability and was launched into the market in 2010. However, the effect of posture - to
our knowledge - has not yet been studied. The change of body positioning during surgery is
regularly necessary in order to improve surgical access to anatomic structures. These
alterations in positioning are known to be accompanied by changes in haemodynamic
parameters.
The aim of this study was to evaluate the ANI in patients undergoing elective surgery in
lithotomy position.
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Observational Model: Case Control, Time Perspective: Prospective
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