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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT03907722
Other study ID # IndonesianCRC2
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2018
Est. completion date September 3, 2018

Study information

Verified date April 2019
Source Indonesian Cardiovascular Research Center
Contact n/a
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

The investigators enrolled 217 patients with acute STEMI undergoing primary PCI. The rs2305619 polymorphism was evaluated by real time PCR and plasma PTX3 concentration was assessed by human PTX3 ELISA kit.


Description:

The investigators enrolled 217 patients with acute STEMI undergoing primary PCI in a tertiary care academic cardiovascular center. The rs2305619 polymorphism was evaluated by real time PCR and plasma PTX3 concentration was assessed by human PTX3 ELISA kit. The primary outcome of the study was the incidence of coronary microvascular obstruction defined as thrombolysis in myocardial infarction (TIMI) grade <3 flow after primary PCI or TIMI grade 3 flow with myocardial blush grade 0 or 1. Patients were grouped based on the genotypic variants (AA, AG and GG). The primary outcome was compared among the three variants, as well as the PTX3 concentration and 30-day mortality.


Recruitment information / eligibility

Status Completed
Enrollment 217
Est. completion date September 3, 2018
Est. primary completion date August 2, 2018
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- Patients with acute STEMI with symptom onset <12 h and treated by primary PCI

Exclusion Criteria:

- STEMI patients who received fibrinolytic therapy

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Long pentraxin 3
Primary PCI

Locations

Country Name City State
Indonesia Indonesian Cardiovascular Research Center Jakarta DKI Jakarta

Sponsors (1)

Lead Sponsor Collaborator
Indonesian Cardiovascular Research Center

Country where clinical trial is conducted

Indonesia, 

Outcome

Type Measure Description Time frame Safety issue
Primary Incidence of microvascular obstruction Percentage Immediate after pci
Secondary Incidence of mortality Percentage 30 days
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