Solid Tumors Clinical Trial
Official title:
Phase I/II Study Using Epitope Peptide Restricted to HLA-A*24 or HLA-A*02 in Patients With Advanced Solid Tumors That Are Refractory to Standard Therapy
In this study, the investigators examine using a combination of two types of HLA-A*2402 (or HLA-A*0201)-restricted epitope peptides, which were derived from VEGF-R1 and VEGF-R2 the safety, immunogenicity, and antitumor effect of vaccine treatment for advanced solid tumor patients who are refractory to standard therapy.
The purpose of this study is to evaluate the safety, tolerability, immune response and
clinical efficacies of HLA-A*2402 or HLA-A*0201 restricted epitope peptides (VEGF-R1 and
VEGF-R2) emulsified with Montanide ISA 51 for advanced solid tumors.
In this phase I/II trial, the investigators examine using a combination of the two peptides
the safety, immunogenicity, and antitumor effect of vaccine treatment for HLA-A*2402 or
HLA-A*0201-positive advanced solid tumor patients who are refractory to standard therapy.
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Status | Clinical Trial | Phase | |
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Active, not recruiting |
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