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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LB4330 in Patients With Advanced Solid Tumors（MEETCD8-001） — MEETCD8-001  

Solid Tumor Clinical Trial

Official title:
A Phase I，Dose Escalation and Expansion Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LB4330 in Patients With Advanced Solid Tumors（MEETCD8-001）

Clinical Trial Summary

This is a Phase I study designed to evaluate if LB4330, an anti-Claudin 18.2 and CD8 T cell activator fusion protein, is safe, tolerable and efficacious in participants with Advanced Solid Tumors

Clinical Trial Description

This first time in patients, open-label, multi-center study will have LB4330 administered intravenously (IV) in Patients with Advanced Solid Tumors. This study will have 2 parts: Part A which will have dose escalation cohorts and Part B which will have the dose expansion cohorts. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05707676
Study type Interventional
Source L & L biopharma Co., Ltd., Shanghai China
Contact Yan Luan, Doctor
Phone 86-21-54152522
Email luanyn2@lnlbio.com
Status Recruiting
Phase Phase 1
Start date November 30, 2022
Completion date September 2026
View Details
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