Muscle Growth Following a Resistance Training Program in Men and Women Consuming Protein Supplements

Skeletal Muscle Growth Clinical Trial

Official title:

Muscle Growth and Development Following a 12-week Resistance Training Program in Men and Women Consuming Soy and Whey Protein Supplements

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03868631
• Other study ID #: 01435225
• Status: Completed
• Phase: N/A
• Start date: August 15, 2016
• Est. completion date: April 30, 2017

Study information

• Verified date: February 2020
• Source: Point Loma Nazarene University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Soy and whey protein have different concentrations of leucine, an amino acid known to be a particularly potent simulator of muscle protein synthesis. The purpose of this study is to determine whether matching soy and whey protein supplements for leucine content instead of by total protein content would contribute to differences in strength increases and muscle growth in response to 12 wk of resistance training.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 61
• Est. completion date: April 30, 2017
• Est. primary completion date: April 30, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• non-smoking

• body mass index (BMI) 18.5-24.9

• recreationally active

Exclusion Criteria:

• participated in structured weight training during the previous 12 month

• vegetarian or vegan

• presence of chronic disease

• pregnant, postpartum up to six months, lactating, or intention to become pregnant

• allergy to whey or soy

• changes in body weight more than 10 pounds in the past three months

Related Conditions & MeSH terms

• Skeletal Muscle Growth

Intervention

Dietary Supplement:
• Whey protein supplement
19 g whey protein isolate (contains 2 g leucine) was consumed daily by one intervention group.
• Soy protein supplement
26 g soy protein isolate (contains 2 g leucine) was consumed daily by the other intervention group.

Locations

Country	Name	City	State
United States	Arizona State University	Phoenix	Arizona

Sponsors (1)

Lead Sponsor	Collaborator
Point Loma Nazarene University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Lean Body Mass Change	assessed using dual energy x-ray absorptiometry (DEXA) scan for changes in lean body mass (kg)	Post-12 week intervention
Primary	Muscle Tissue Thickness Change	assessed using changes in muscle thickness assessed by ultrasound (cm)	Post-12 week intervention
Primary	Leg Girth Changes	assessed using circumference measurements (cm)	Post-12 week intervention
Secondary	Change in Peak Torque When Doing Leg Extensions	Assessed using an isokinetic dynamometer set at 60 degrees of motion per second (d/s)	Post-12 week intervention