Clinical Trials Logo

Clinical Trial Summary

SevEos is a cross-sectional, multi-center, non-interventional study aimed to describe the treatment patterns in 250 severe asthma patients across the Gulf region. In addition, the study will determine the current level of asthma control and quality of life in these patients; describe the exacerbation patterns; and determine the current levels of blood eosinophils for the enrolled patients.


Clinical Trial Description

The primary objective of this study is to describe the treatments patterns of severe asthmatic patients across four Gulf countries during the past year.

Secondary Objectives

1. To determine the current level of asthma control in these patients. In addition, a comparison of uncontrolled asthma between those with a eosinophilic count ≥ 300 cell/μl and those with an elevated eosinophilic count less than that.

2. To determine the current and past year levels of blood eosinophils, and the percentage of patients with elevated eosinophilic level ≥ 150 cells/μL and ≥ 300 cells/μL

3. To describe the frequency of exacerbations during the past year.

4. To assess the current quality of life (QoL) of these patients.

5. To determine the past year levels of serum IgE.

6. Exploratory objective: To determine the past year levels of other inflammatory biomarkers like periostin and fraction of exhaled nitric oxide (FeNO). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03387722
Study type Observational
Source AstraZeneca
Contact AstraZeneca Clinical Study Information Center
Phone 1-877-240-9479
Email information.center@astrazeneca.com
Status Recruiting
Phase
Start date December 31, 2017
Completion date December 31, 2018

See also
  Status Clinical Trial Phase
Recruiting NCT03377920 - Predictive Value of Spirometric PIF to Produce PIF Rate Needed for the Use of Current DPI's. N/A
Active, not recruiting NCT02038374 - Clinico-biological Correlation of Severe Asthma in Children N/A
Active, not recruiting NCT02114034 - Cohort Analysis of Clinical and Biological Severe Childhood Asthma N/A
Not yet recruiting NCT03532685 - Clinical, Inflammatory and Functional Evaluation of a Population of Severe and Obese Asthmatics: Follow up N/A
Recruiting NCT03608566 - Russian Severe Asthma Registry
Not yet recruiting NCT03476109 - Study of Magnitude and Prediction of Response to Omalizumab and Mepolizumab in Adult Severe Asthma. Phase 4
Completed NCT00621946 - Treatment of Outpatients With Severe Asthma and Moderate or Severe Major Depressive Disorder Phase 4
Not yet recruiting NCT01961258 - "SEVERE ASTHMA" in the COMMUNITY N/A
Withdrawn NCT02433535 - Trial of Simvastatin for the Treatment of Severe Asthma Phase 2
Recruiting NCT02975284 - Unraveling Targets of Therapy in Bronchial Thermoplasty in Severe Asthma (TASMA) Extension Study
Recruiting NCT03361111 - BIOmarkers in Severe AsthMa Patients on Omalizumab Treatment
Recruiting NCT03629782 - Description/Characterisation of Asthmatics Eligible for Biologic Therapy Referral in Prim. and Sec. Care in Europe
Not yet recruiting NCT03435237 - Phenotyping Asthma for Bronchial Thermoplasty N/A
Recruiting NCT03065920 - African Severe Asthma Program: A Research Network for Characterisation of Severe Asthma in Africans (ASAP) N/A
Active, not recruiting NCT01350336 - Bronchial Thermoplasty in Severe Persistent Asthma N/A
Completed NCT03074942 - Reslizumab in Patients With Severe Asthma Who Failed to Respond to Omalizumab Phase 2