Septic Shock Clinical Trial
Official title:
Barrier Function and Production of Inflammatory Cytokines in the Rectal Mucosa in Patients With Septic Shock
Life-threatening infection impairs bloodflow to the gut, thereby causing less delivery of
oxygen. This leads to increased formation of different inflammatory and infectious markers.
The investigators hypothesize, therefore, that there is a significant difference in the
concentrations of inflammatory and infectious markers in the rectal mucosa between patients
with septic shock and healthy controls.
| Status | Not yet recruiting |
| Enrollment | 30 |
| Est. completion date | |
| Est. primary completion date | |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - Septic shock Exclusion Criteria: - Age < 18 years - No next of kin - Pathology of the descending or sigmoid colon or rectum - Pregnancy - 1st degree relatives with inflammatory bowel disease - Severe coagulopathy |
Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| Denmark | Dept. of Intensive Care 4131 | Copenhagen |
| Lead Sponsor | Collaborator |
|---|---|
| Herlev Hospital |
Denmark,
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