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Clinical Trial Summary

The study is aimed to assess the severities of hyperprolactinemia caused by antipsychotic drugs and the effects of the duration of hyperprolactinemia on bone metabolism in schizophrenia patients.


Clinical Trial Description

Hyperprolactinemia is a common adverse effect of antipsychotic drugs. Studies have shown that hyperprolactinemia may affect bone metabolism through direct and indirect effects and increase the risk of osteoporosis and fracture.The investigators assess the duration, the severity of hyperprolactinemia and its effects on bone metabolism in schizophrenics taking antipsychotic drugs through analyzing the correlation between prolactin levels and biochemical markers of bone metabolism and the correlation between the duration of hyperprolactinemia and abnormal bone metabolism. Meanwhile, the investigators aims to obtain the boundary value of prolactin levels in patients with abnormal bone metabolism. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03675750
Study type Observational
Source Shanghai Mental Health Center
Contact LiHua Wang
Phone 18017311510
Email ashleyzhima@163.com
Status Recruiting
Phase
Start date July 1, 2018
Completion date October 31, 2020

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