The Effects of Acthar on Synovial Inflammation in Rheumatoid Arthritis

Status Active, not recruiting

Clinical Trial Summary

Clinical Trial Description

Patients will be assigned to receive either Depo Medrol or Acthar treatment. A synovial biopsy, blood draws, synovial fluid aspiration, and physician assessments will be performed before and after initiating treatment. At screening visit, inclusion and exclusion criteria will be assessed. If assessments have not been completed to verify these criteria, they will be performed at this visit. After patients are confirmed to meet criteria, patient disease activity will be assessed and blood draw, synovial aspiration, and biopsy will be performed before first treatment injection. About 5 days after this first treatment injection, these assessment and samples will be performed again. About 5-6 weeks after first treatment injection, a final physician assessment will be performed. Patients will have the option of consenting to allow storage of samples for future research. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03511625
Study type	Interventional
Source	Attune Health Research, Inc.
Contact
Status	Active, not recruiting
Phase	Phase 3
Start date	October 2, 2018
Completion date	December 3, 2024

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