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Resuscitation clinical trials

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NCT ID: NCT06280118 Completed - Resuscitation Clinical Trials

The Effect of Fatigue on CPR

Start date: April 20, 2023
Phase: N/A
Study type: Interventional

Background: This study, in contrast to the previous studies, generated a scenario of fatigue in an earthquake scenario and aimed to measure the effect of fatigue on the quality of cardiopulmonary resuscitation (CPR) performed by paramedics in a debris course. Methods: The study was designed as a randomized controlled trial. The sample, consisting of 84 paramedic students, was randomly assigned as 42 control and 42 experimental groups. Fatigue was created in the participants by rehearsing the process of removing and transporting earthquake victims from the rubble through the prepared track. A personal information form and a CPR measurement form were used to obtain the data. The simulator was used to evaluate the accuracy of CPR. The collected data were analysed with the statistical program.

NCT ID: NCT06254651 Completed - Resuscitation Clinical Trials

Resuscitation Table Height for Face-mask Ventilation in Infants

ForTab
Start date: February 12, 2024
Phase: N/A
Study type: Interventional

Positive pressure ventilation (PPV) is the most important intervention in neonatal resuscitation. During PPV, it is important to hold the face-mask with care, as applying excessive pressure could cause injury to the infant, while insufficient pressure could be a contributor of mask leak and reduced effective ventilation. Application of positive pressure to face structures may trigger a vagally mediated reflex via the trigeminal nerve that innervates the skin of the face leading to apnoea and a decrease in heart rate (TCR, trigeminal-cardiac reflex). The force exerted by providers during neonatal ventilation to improve mask seal might result in pressure lesions and the elicitation of the trigeminal-cardiac reflex. The height of the resuscitation could influence the forces applied to the face and the quality of the procedure. Information about the applied forces in relation to the height of the resuscitation table is unknown.

NCT ID: NCT06182007 Completed - Cardiac Arrest Clinical Trials

Post-Resuscitation Pneumothorax - Analysis of Incidence, Risk Factors and Outcome Relevance

Start date: February 2, 2020
Phase:
Study type: Observational

In this retrospective study, the investigators seek to investigate the incidence of pneumothorax following possible risk factors, and elucidate its association with outcomes.

NCT ID: NCT06122909 Recruiting - Septic Shock Clinical Trials

The Effect Of Resuscitation Guided By Two Different Dynamic Parameters On Time To Normalization Of The Capillary Refill Time In Adult Patients With Septic Shock

Start date: July 21, 2023
Phase: Phase 3
Study type: Interventional

The aim of this study is to compare the effect of resuscitation guided by Left ventricular outflow tract-velocity time integral (LVOT-VTI) variation versus the effect of resuscitation guided by inferior vena cava (IVC) variation on time to normalization of the capillary refill time in adult patients with septic shock, amount of resuscitation fluids, rate of vasopressor and ICU length of stay.

NCT ID: NCT06070077 Completed - Resuscitation Clinical Trials

CPR Quality in Via Ferrata Rescues

Start date: October 3, 2023
Phase:
Study type: Observational

This study evaluates the effectiveness of CPR during via ferrata rescues, focusing on response quality and outcomes in challenging outdoor settings.

NCT ID: NCT05709665 Recruiting - Resuscitation Clinical Trials

Incidence of the Out- and in Hospital Cardiac Arrest at a Tertiary Hospital in Germany

ProseCPR
Start date: January 11, 2023
Phase:
Study type: Observational

Incidence of the background information, incidence and special characteristics of out- and in-hospital cardiac arrest at a tertiary hospital in Germany.

NCT ID: NCT05709613 Completed - Cardiac Arrest Clinical Trials

Use of a Feedback Device to Limit Too Shallow Compressions Associated With the Use of an I-gel® Device

Start date: January 30, 2023
Phase: N/A
Study type: Interventional

Airway management in out-of-hospital cardiac arrest is still debated. Several options exist: bag-valve-mask ventilation, supraglottic devices and endotracheal intubation. Intermediate and advanced airway management strategies could be useful devices to increase chest compression fraction. A previous study shows that early insertion of an i-gel device significantly increases chest compression fraction and enhances respiratory parameters. However, the compressions were found to be shallower in the experimental group using the i-gel device. Although, the shallower compressions found in the supraglottic airway device group did not appear to be linked to their provision in an over-the-head position, it is reasonable to assume that the addition of a feedback device to the use of an i-gel® device could fix this issue. The feedback devices seem to be able to provide a benefit, and allow deeper compressions / more often in the depth target. There is a mismatch between perceived and actual cardiopulmonary resuscitation performance supporting the need for such a feedback device's study.

NCT ID: NCT05551312 Enrolling by invitation - Resuscitation Clinical Trials

Mobile Virtual Simulation Training in Essential Newborn Care for Healthcare Workers in Low and Middle Income Countries

Start date: December 1, 2022
Phase: N/A
Study type: Interventional

Intrapartum asphyxia and prematurity are the leading causes of neonatal mortality in low and middle income countries. Neonatal resuscitation training reduces asphyxia-related newborn mortality and morbidity, but in the absence of continuing low-dose, high frequency practice, these initial gains rapidly decay. The investigators propose to develop and evaluate innovative mobile virtual simulations for refresher training on neonatal resuscitation and essential newborn care to support the retention of knowledge and skills among health care workers in low and middle income countries.

NCT ID: NCT05498402 Completed - Cardiac Arrest Clinical Trials

Effect of IAM With an I-gel® on Ventilation Parameters in Simulated Pediatric OHCA

Start date: January 30, 2023
Phase: N/A
Study type: Interventional

Pediatric cardiac arrest occurs most in the prehospital setting. Most of them are due to respiratory failure (e.g., trauma, drowning, respiratory distress), where hypoxia leads to cardiac arrest. Generally, emergency medical services (EMS) first use basic airway management techniques i.e., the use of a bag-valve-mask (BVM) device, to restore oxygenation in pediatric OHCA victims. However, these devices present many drawbacks and limitations. Intermediate airway management, i.e., the use of SGA devices, especially the i-gel® has several advantages. It has been shown to enhance both circulatory and ventilatory parameters. There is increasing evidence that IAM devices can safely be used in children. In two pediatric studies of OHCA, American paramedics had significantly higher success rates with SGA devices than with TI. A neonatal animal model showed that the use of SGA was feasible and non-inferior to TI in this population. However, data regarding the effect of IAM with an i-gel® versus the use of a BVM on ventilation parameters during pediatric OHCA is missing. The hypothesis underlying this study is that, in case of pediatric OHCA, early insertion of an i-gel® device without prior BVM ventilation should improve ventilation parameters in comparison with the standard approach consisting in BVM ventilations.

NCT ID: NCT05474170 Completed - Pediatric ALL Clinical Trials

Impact of 2 Resuscitation Sequences on Management of Simulated Pediatric Cardiac Arrest

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

The International Liaison Committee on Resuscitation regularly publishes a Consensus on Science with Treatment Recommendations but guidelines can nevertheless differ when knowledge gaps persist. In case of pediatric cardiac arrest, the American Heart Association recommends following the adult resuscitation sequence i.e., starting with chest compressions. Conversely, the European Resuscitation Council advocates the delivery of 5 initial rescue breaths before starting chest compressions. Carrying out a randomized trial in children in cardiac arrest to assess the impact of these strategies would prove particularly challenging and ethical concerns may prevent such a trial from being performed. This will be a superiority, cross-over randomized trial whose goal is to determine the impact of these 2 resuscitation sequences on alveolar ventilation in a pediatric model of cardiac arrest. While not definitive, its results could help fill part of the current knowledge gap.